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Prostacyclin

Start up: A French program to support patients with pulmonary arterial hypertension during the adjustment of prostanoids to the individualized optimal dose

Emmanuel Bergot, Marie Fertin, Mélanie Gallant Dewavrin, Grégoire Prévot, Julia Meijer, Coralie Hakibilen, Laurette Gruand, Sophie Gauthier, Andreea Todea, Thamer Boukerzaza, Xavier Jaïs

published 29 Oct 2025

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Vascular imbalance in polycystic ovary syndrome: Insights into endothelial dysfunction

Tuğba Raika Kıran, Mehmet Erdem, Engin Yıldırım, Feyza İnceoğlu

published 05 Sep 2025

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The selective PGI₂ receptor agonist selexipag ameliorates Sugen 5416/hypoxia-induced pulmonary arterial hypertension in rats

Yohei Honda, Keiji Kosugi, Chiaki Fuchikami, Kazuya Kuramoto, Yuki Numakura, Keiichi Kuwano

published 15 Oct 2020

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Hospital burden of pulmonary arterial hypertension in France

Emmanuel Bergot, Lucie De Leotoing, Hakim Bendjenana, Charlène Tournier, Alexandre Vainchtock, Gaëlle Nachbaur, Marc Humbert

published 19 Sep 2019

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Mechanism of anti-remodelling action of treprostinil in human pulmonary arterial smooth muscle cells

Christopher Lambers, Christoph Kornauth, Felicitas Oberndorfer, Panja M. Boehm, Michael Tamm, Walter Klepetko, Michael Roth

published 01 Nov 2018

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Prostacyclin, thromboxane and glomerular filtration rate are abnormal in sickle cell pregnancy

Opeyemi Abayomi Obilade, Alani Suleimon Akanmu, Fiona Broughton Pipkin, Bosede Bukola Afolabi

published 07 Sep 2017

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Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor

Sorin Tunaru, Ramesh Chennupati, Rolf M. Nüsing, Stefan Offermanns

published 23 Sep 2016

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Enhanced Pulmonary Vascular and Alveolar Development via Prenatal Administration of a Slow-Release Synthetic Prostacyclin Agonist in Rat Fetal Lung Hypoplasia

Satoshi Umeda, Shigeru Miyagawa, Satsuki Fukushima, Noriko Oda, Atsuhiro Saito, Yoshiki Sakai, Yoshiki Sawa, Hiroomi Okuyama

published 16 Aug 2016

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Reversal of MicroRNA Dysregulation in an Animal Model of Pulmonary Hypertension

Igor B. Gubrij, Amanda K. Pangle, Li Pang, Larry G. Johnson

published 27 Jan 2016

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Long Lasting Microvascular Tone Alteration in Rat Offspring Exposed In Utero to Maternal Hyperglycaemia

Emilie Vessières, Abdallah Dib, Jennifer Bourreau, Eric Lelièvre, Marc-Antoine Custaud, Martine Lelièvre-Pégorier, Laurent Loufrani, Daniel Henrion, Céline Fassot

published 12 Jan 2016

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COX-2 Protects against Atherosclerosis Independently of Local Vascular Prostacyclin: Identification of COX-2 Associated Pathways Implicate Rgl1 and Lymphocyte Networks

Nicholas S. Kirkby, Martina H. Lundberg, William R. Wright, Timothy D. Warner, Mark J. Paul-Clark, Jane A. Mitchell

published 02 Jun 2014

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Prostacyclin Analogue Beraprost Inhibits Cardiac Fibroblast Proliferation Depending on Prostacyclin Receptor Activation through a TGF β-Smad Signal Pathway

Yun Chen, Shengju Yang, Wenjuan Yao, Hongyan Zhu, Xiaole Xu, Guoliang Meng, Wei Zhang

published 22 May 2014

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Cyclic Nucleotide Dependent Dephosphorylation of Regulator of G-Protein Signaling 18 in Human Platelets

Kristina Gegenbauer, Zoltan Nagy, Albert Smolenski

published 07 Nov 2013

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