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Post-translational modification

The impact of apolipoprotein E, type ∊4 allele on Alzheimer’s disease pathological biomarkers: a comprehensive post-mortem pilot-analysis

Ziyu Wan, Tao Ma

published 06 Feb 2025

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Effects of treadmill running on anxiety- and craniofacial pain-like behaviors with histone H3 acetylation in the brain of mice subjected to social defeat stress

Kajita Piriyaprasath, Mana Hasegawa, Yuya Iwamoto, Rantaro Kamimura, Andi Sitti Hajrah Yusuf, Noritaka Fujii, Kensuke Yamamura, Keiichiro Okamoto

published 27 Jan 2025

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Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions

Zac Sandy, Zijuan Wang, Deepak Behera, Benjamin M. Foster, Finlay A. Martin, Kira Brüninghoff, Kathleen M. Cain, Wolfgang Dörner, Maria Jose Cabello-Lobato, Josep V. Forment, Matthew J. Cliff, Igor Larrosa, Perdita Barran, Duncan L. Smith, Henning D. Mootz, Christine K. Schmidt

published 27 Jan 2025

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Activation of S1PR2 on macrophages and the hepatocyte S1PR2/RhoA/ROCK1/MLC2 pathway in vanishing bile duct syndrome

Aya Miyagawa-Hayashino, Tetsuya Imura, Toshiaki Takezawa, Maki Hirai, Saya Shibata, Hiroshi Ogi, Takahiro Tsujikawa, Eiichi Konishi

published 24 Jan 2025

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Tandem mass tag-based quantitative proteomics and targeted hormone analysis reveal the response to insect herbivory stress in Ginseng (Panax ginseng, L.)

Haitao Li, Lixin Zhang, Xiang Han, Qi Zhang, Guangna Liu, Guofeng Zhang, Yurong Zhu, Hongyang Liu, Haowei Deng, Shuangli Liu, Guangsheng Xi

published 22 Jan 2025

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Inhibition of the anti-apoptotic protein BCL2 in EML4-ALK cell models as a second proposed therapeutic target for non-small cell lung cancer

Richard Junior Zapata Dongo, Diletta Fontana, Luca Mologni, Juan Enrique Faya Castillo, Stefany Fiorella Infante Varillas

published 21 Jan 2025

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Signalling pathways involved in urotensin II induced ventricular myocyte hypertrophy

Hadeel S. Al Ali, Glenn C. Rodrigo, David G. Lambert

published 16 Jan 2025

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Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase

Sean J. Ezekiel, Mackenzie Searle, Jaeok Park

published 15 Jan 2025

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Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways

Binmei Zhang, Jingxiu Hou, Jiaren Liu, Junhui He, Yunan Gao, Guangnan Li, Tianjiao Ma, Xin Lv, Li Dong, Wei Yang

published 08 Jan 2025

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In vitro and in silico analyses of amino acid substitution effects at the conserved N-linked glycosylation site in hepatitis B virus surface protein on antigenicity, immunogenicity, HBV replication and secretion

Patcharin Tepjanta, Thammakorn Saethang, Kazuhito Fujiyama, Ryo Misaki, Ingorn Kimkong

published 06 Jan 2025

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High glucose couples DJ-1 with PTEN to activate PDGFRβ for renal proximal tubular cell injury

Falguni Das, Nandini Ghosh-Choudhury, Balakuntalam S. Kasinath, Kumar Sharma, Goutam Ghosh Choudhury

published 06 Jan 2025

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Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation

Michael O. Isei, Meredith Crockett, Emily Chen, Joel Rodwell-Bullock, Trae Carroll, Peter A. Girardi, Keith Nehrke, Gail V. W. Johnson

published 03 Jan 2025

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Site-specific prediction of O-GlcNAc modification in proteins using evolutionary scale model

Ayesha Khalid, Afshan Kaleem, Wajahat Qazi, Roheena Abdullah, Mehwish Iqtedar, Shagufta Naz

published 31 Dec 2024

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