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Post-translational modification

Lymphoma and Myeloma Cell Resistance to Cytotoxic Agents and Ionizing Radiations Is Not Affected by Exposure to Anti–IL-6 Antibody

Angélique Gougelet, Adeline Mansuy, Jean-Yves Blay, Laurent Alberti, Claudine Vermot-Desroches

published 30 Nov 2009

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Positive Regulatory Control Loop between Gut Leptin and Intestinal GLUT2/GLUT5 Transporters Links to Hepatic Metabolic Functions in Rodents

Yassine Sakar, Corinne Nazaret, Philippe Lettéron, Amal Ait Omar, Mathilde Avenati, Benoît Viollet, Robert Ducroc, André Bado

published 30 Nov 2009

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Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase

Rekha Pattanayek, Tetsuya Mori, Yao Xu, Sabuj Pattanayek, Carl H. Johnson, Martin Egli

published 26 Nov 2009

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A Predictive Phosphorylation Signature of Lung Cancer

Chang-Jiun Wu, Tianxi Cai, Klarisa Rikova, David Merberg, Simon Kasif, Martin Steffen

published 25 Nov 2009

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Intramolecular Regulation of Phosphorylation Status of the Circadian Clock Protein KaiC

Yao Xu, Tetsuya Mori, Ximing Qin, Heping Yan, Martin Egli, Carl Hirschie Johnson

published 25 Nov 2009

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Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses

Lina Han, Albertus T. J. Wierenga, Marjan Rozenveld-Geugien, Kim van de Lande, Edo Vellenga, Jan Jacob Schuringa

published 24 Nov 2009

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Insulin Signaling Regulates Mitochondrial Function in Pancreatic β-Cells

Siming Liu, Terumasa Okada, Anke Assmann, Jamie Soto, Chong Wee Liew, Heiko Bugger, Orian S. Shirihai, E. Dale Abel, Rohit N. Kulkarni

published 24 Nov 2009

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Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease

Yazi D. Ke, Fabien Delerue, Amadeus Gladbach, Jürgen Götz, Lars M. Ittner

published 19 Nov 2009

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Dramatic Co-Activation of WWOX/WOX1 with CREB and NF-κB in Delayed Loss of Small Dorsal Root Ganglion Neurons upon Sciatic Nerve Transection in Rats

Meng-Yen Li, Feng-Jie Lai, Li-Jin Hsu, Chen-Peng Lo, Ching-Li Cheng, Sing-Ru Lin, Ming-Hui Lee, Jean-Yun Chang, Dudekula Subhan, Ming-Shu Tsai, Chun-I Sze, Subbiah Pugazhenthi, Nan-Shan Chang, Shur-Tzu Chen

published 12 Nov 2009

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Evidence for Impaired CARD15 Signalling in Crohn's Disease without Disease Linked Variants

Jakob Benedict Seidelin, Oliver Jay Broom, Jørgen Olsen, Ole Haagen Nielsen

published 12 Nov 2009

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Oxidative Stress Impairs the Heat Stress Response and Delays Unfolded Protein Recovery

Masaaki Adachi, Yaohua Liu, Kyoko Fujii, Stuart K. Calderwood, Akira Nakai, Kohzoh Imai, Yasuhisa Shinomura

published 11 Nov 2009

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Oncogenic RAS Enables DNA Damage- and p53-Dependent Differentiation of Acute Myeloid Leukemia Cells in Response to Chemotherapy

Mona Meyer, Daniela Rübsamen, Robert Slany, Thomas Illmer, Kathleen Stabla, Petra Roth, Thorsten Stiewe, Martin Eilers, Andreas Neubauer

published 05 Nov 2009

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Stringency of the 2-His–1-Asp Active-Site Motif in Prolyl 4-Hydroxylase

Kelly L. Gorres, Khian Hong Pua, Ronald T. Raines

published 05 Nov 2009

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