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Post-translational modification

Protopanaxadiol stimulates glucose consumption by modulating the AMP-activated protein kinase pathway in myotubes, hepatoma cells, and adipocytes

Dahae Lee, Sang Hee Shim, Ki Sung Kang

published 29 Jul 2025

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Response Gene to Complement 32 promotes cell proliferation and tamoxifen resistance in breast cancer via elevated FoxM1 expression

Xinlei Li, Yan Liu, Zhiqian Wang, Xiaocui Bu, Yu Wang, Wei Zhang, Peng Zhao

published 28 Jul 2025

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Phosphatidylcholine suppresses inflammatory responses in LPS-stimulated MG6 microglial cells by inhibiting NF-κB/JNK/p38 MAPK signaling

Sachiko Mizuno, Yuki Kurobe-Takashima, Daisuke Kuriki, Kenta Susaki, Kurataka Otsuka, Tomoko Tsuchihashi, Keiko Abe, Shoko Kobayashi

published 28 Jul 2025

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Cloning and enhancing lumbrokinase production from local Eisenia fetida by signal peptide engineering for effective thrombosis treatment

Adeeba Tabassum, Nadia Zeeshan, Amber Afroz

published 24 Jul 2025

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The role of advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) in hypertrophic obstructive cardiomyopathy

Shengxu Li, Xuanye Bi, Quanxu An, Yuhang Li, Yazhe Tang

published 24 Jul 2025

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Integrated bioinformatics and experimental validation identify ATF3 as a key gene in secondary brain damage after intracerebral hemorrhage

Tao Cui, Jinbang Huang, Chaoyong Zhang, Bin Wang

published 18 Jul 2025

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Cysteine pattern barcoding-based dataset filtration enhances the machine learning-assisted interpretation of Conus venom peptide therapeutics

Rimsha Bibi, Noshaba Qasmi, Sajid Rashid

published 11 Jul 2025

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MTMR7 regulates human spermatogonial stem cells proliferation and migration via targeting FLNB

Nianchao Zhou, Tiantian Wu, Yi Yu, Wenxin Gao, Bing Jiang, Haoyue Hu, Xiaoyan Huang, Cong Shen, Yibo Wu, Tingting Gao

published 10 Jul 2025

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Deep crypt secretory cells shape region-specific mucin glycosylation patterns in the mouse colon

Daisuke Sugahara, Hayato Kawakami, Yoshihiro Akimoto

published 08 Jul 2025

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Proteomic and phosphoproteomic analysis of rabies pathogenesis in the clinical canine brain and identification of a kinase inhibitor as a potential repurposed antiviral agent

Peerut Chienwichai, Kunjimas Ketsuwan, Boonlert Lumlertdacha, Chanon Fa-Ngoen, Punchaya Supasawat, Rojjanaporn Pulmanausahakul, Promsin Masrinoul, Tipparat Thiangtrongjit, Onrapak Reamtong

published 27 Jun 2025

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Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA-A0201

Shan Jiang, Zhaoqian Su, Nathaniel Bloodworth, Yunchao Liu, Cristina E. Martina, David G. Harrison, Jens Meiler

published 27 Jun 2025

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Identification and mitigation of blood’s interference with the antimicrobial activity of AgNbO₃ particles

Cyrus Talebpour, Fereshteh Fani, Marc Ouellette, Marilynn Fairfax, Houshang Alamdari, Hossein Salimnia

published 24 Jun 2025

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Prostaglandin E₂ dependent migration of human brain endothelial cells is mediated through Rho-Kinase-II

Gausal Azam Khan, Arjun Ghosh

published 23 Jun 2025

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