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Post-translational modification

Reciprocal Allosteric Modulation of Carbon Monoxide and Warfarin Binding to Ferrous Human Serum Heme-Albumin

Alessio Bocedi, Giampiero De Sanctis, Chiara Ciaccio, Grazia R. Tundo, Alessandra Di Masi, Gabriella Fanali, Francesco P. Nicoletti, Mauro Fasano, Giulietta Smulevich, Paolo Ascenzi, Massimo Coletta

published 21 Mar 2013

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Toxoplasma gondii Triggers Phosphorylation and Nuclear Translocation of Dendritic Cell STAT1 while Simultaneously Blocking IFNγ-Induced STAT1 Transcriptional Activity

Anne G. Schneider, Delbert S. Abi Abdallah, Barbara A. Butcher, Eric Y. Denkers

published 20 Mar 2013

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Free Fatty Acid Induces Endoplasmic Reticulum Stress and Apoptosis of β-cells by Ca²⁺/Calpain-2 Pathways

Wei Cui, Jie Ma, Xingqin Wang, Wenjuan Yang, Jing Zhang, Qiuhe Ji

published 20 Mar 2013

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MicroRNA-181a Suppresses Mouse Granulosa Cell Proliferation by Targeting Activin Receptor IIA

Qun Zhang, Haixiang Sun, Yue Jiang, Lijun Ding, Shaogen Wu, Ting Fang, Guijun Yan, Yali Hu

published 20 Mar 2013

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The IKK Inhibitor Bay 11-7082 Induces Cell Death Independent from Inhibition of Activation of NFκB Transcription Factors

Hilka Rauert-Wunderlich, Daniela Siegmund, Eduard Maier, Tina Giner, Ralf C. Bargou, Harald Wajant, Thorsten Stühmer

published 20 Mar 2013

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Glyceraldehyde-3-Phosphate Dehydrogenase Interacts with Proapoptotic Kinase Mst1 to Promote Cardiomyocyte Apoptosis

Bei You, Shengdong Huang, Qing Qin, Bing Yi, Yang Yuan, Zhiyun Xu, Jianxin Sun

published 20 Mar 2013

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Inhibition of Histone Deacetylase Impacts Cancer Stem Cells and Induces Epithelial-Mesenchyme Transition of Head and Neck Cancer

Fernanda S. Giudice, Decio S. Pinto Jr, Jacques E. Nör, Cristiane H. Squarize, Rogerio M. Castilho

published 20 Mar 2013

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Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold?

George V. Aslanidi, Angela E. Rivers, Luis Ortiz, Liujiang Song, Chen Ling, Lakshmanan Govindasamy, Kim Van Vliet, Mengqun Tan, Mavis Agbandje-McKenna, Arun Srivastava

published 19 Mar 2013

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The Protein Kinase TPL2 Is Essential for ERK1/ERK2 Activation and Cytokine Gene Expression in Airway Epithelial Cells Exposed to Pathogen-Associated Molecular Patterns (PAMPs)

Guy Martel, Julie Bérubé, Simon Rousseau

published 19 Mar 2013

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Phylogenetic and Molecular Characterization of the Splicing Factor RBM4

Chia-Chen Lu, Tz-Hao Chen, Jhe-Rong Wu, Hung-Hsi Chen, Hsin-Yi Yu, Woan-Yuh Tarn

published 19 Mar 2013

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Identification of Small Molecule Activators of BMP Signaling

Karen Vrijens, Wenwei Lin, Jimmy Cui, Dana Farmer, Jonathan Low, Elodie Pronier, Fu-Yue Zeng, Anang A. Shelat, Kiplin Guy, Michael R. Taylor, Taosheng Chen, Martine F. Roussel

published 19 Mar 2013

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The Structure of HasB Reveals a New Class of TonB Protein Fold

Gisele Cardoso de Amorim, Ada Prochnicka-Chalufour, Philippe Delepelaire, Julien Lefèvre, Catherine Simenel, Cécile Wandersman, Muriel Delepierre, Nadia Izadi-Pruneyre

published 19 Mar 2013

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Glycoform-Selective Prion Formation in Sporadic and Familial Forms of Prion Disease

Xiangzhu Xiao, Jue Yuan, Stéphane Haïk, Ignazio Cali, Yian Zhan, Mohammed Moudjou, Baiya Li, Jean-Louis Laplanche, Hubert Laude, Jan Langeveld, Pierluigi Gambetti, Tetsuyuki Kitamoto, Qingzhong Kong, Jean-Philippe Brandel, Brian A. Cobb, Robert B. Petersen, Wen-Quan Zou

published 19 Mar 2013

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