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Post-translational modification

Overcoming the Refractory Expression of Secreted Recombinant Proteins in Mammalian Cells through Modification of the Signal Peptide and Adjacent Amino Acids

Gülin Güler-Gane, Sara Kidd, [ ... ], Natalie J. Tigue

Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway

Hui H. Zhang, Jingxiang Huang, [ ... ], Brendan D. Manning

SIRT1 Negatively Regulates the Mammalian Target of Rapamycin

Hiyaa Singhee Ghosh, Michael McBurney, Paul D. Robbins

Sorting Signals, N-Terminal Modifications and Abundance of the Chloroplast Proteome

Boris Zybailov, Heidi Rutschow, [ ... ], Klaas J. van Wijk

A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death

Carla Lucia Esposito, Diana Passaro, [ ... ], Laura Cerchia

Hydrogen Peroxide Probes Directed to Different Cellular Compartments

Mikalai Malinouski, You Zhou, [ ... ], Vadim N. Gladyshev

Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics

Marisa K. Joubert, Meghana Deshpande, [ ... ], Vibha Jawa

TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway

Brian Tomkowicz, Eileen Walsh, [ ... ], Timothy McCabe

Effect of Signal Peptide on Stability and Folding of Escherichia coli Thioredoxin

Pranveer Singh, Likhesh Sharma, [ ... ], Raghavan Varadarajan

The Goodwin Model: Behind the Hill Function

Didier Gonze, Wassim Abou-Jaoudé

Comparison of Internal Ribosome Entry Site (IRES) and Furin-2A (F2A) for Monoclonal Antibody Expression Level and Quality in CHO Cells

Steven C. L. Ho, Muriel Bardor, [ ... ], Yuansheng Yang

On the Mechanism of Chloroquine Resistance in Plasmodium falciparum

Mauro Chinappi, Allegra Via, Paolo Marcatili, Anna Tramontano

HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons

Sigeng Chen, Geoffrey C. Owens, Helen Makarenkova, David B. Edelman

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