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Post-translational modification

Molecular Dynamics of CYP2D6 Polymorphisms in the Absence and Presence of a Mechanism-Based Inactivator Reveals Changes in Local Flexibility and Dominant Substrate Access Channels

Parker W. de Waal, Kyle F. Sunden, Laura Lowe Furge

published 06 Oct 2014

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Nuclear Import of Transcription Factor BR-C Is Mediated by Its Interaction with RACK1

Daojun Cheng, Wenliang Qian, Yonghu Wang, Meng Meng, Ling Wei, Zhiqing Li, Lixia Kang, Jian Peng, Qingyou Xia

published 03 Oct 2014

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Characterization of the Neurospora crassa Cell Fusion Proteins, HAM-6, HAM-7, HAM-8, HAM-9, HAM-10, AMPH-1 and WHI-2

Ci Fu, Jie Ao, Anne Dettmann, Stephan Seiler, Stephen J. Free

published 03 Oct 2014

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Study of the Affinity between the Protein Kinase PKA and Peptide Substrates Derived from Kemptide Using Molecular Dynamics Simulations and MM/GBSA

Karel Mena-Ulecia, Ariela Vergara-Jaque, Horacio Poblete, William Tiznado, Julio Caballero

published 02 Oct 2014

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Both Transmembrane Domains of BK β1 Subunits Are Essential to Confer the Normal Phenotype of β1-Containing BK Channels

Guruprasad Kuntamallappanavar, Ligia Toro, Alex M. Dopico

published 02 Oct 2014

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CDCP1 Identifies a CD146 Negative Subset of Marrow Fibroblasts Involved with Cytokine Production

Mineo Iwata, Beverly Torok-Storb, Elizabeth A. Wayner, William G. Carter

published 02 Oct 2014

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Acetate Availability and Utilization Supports the Growth of Mutant Sub-Populations on Aging Bacterial Colonies

Jessica M. Bergman, Marie Wrande, Diarmaid Hughes

published 02 Oct 2014

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Differential Pro-Inflammatory Responses of Astrocytes and Microglia Involve STAT3 Activation in Response to 1800 MHz Radiofrequency Fields

Yonghui Lu, Mindi He, Yang Zhang, Shangcheng Xu, Lei Zhang, Yue He, Chunhai Chen, Chuan Liu, Huifeng Pi, Zhengping Yu, Zhou Zhou

published 02 Oct 2014

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JAK2/STAT3 Inhibition Attenuates Noise-Induced Hearing Loss

Teresa Wilson, Irina Omelchenko, Sarah Foster, Yuan Zhang, Xiaorui Shi, Alfred L. Nuttall

published 02 Oct 2014

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Coenzyme Q₁₀ Protects Human Endothelial Cells from β-Amyloid Uptake and Oxidative Stress-Induced Injury

Mario Durán-Prado, Javier Frontiñán, Raquel Santiago-Mora, Juan Ramón Peinado, Cristina Parrado-Fernández, María Victoria Gómez-Almagro, María Moreno, José Alberto López-Domínguez, José Manuel Villalba, Francisco J. Alcaín

published 01 Oct 2014

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Androgen Suppresses the Proliferation of Androgen Receptor-Positive Castration-Resistant Prostate Cancer Cells via Inhibition of Cdk2, CyclinA, and Skp2

John M. Kokontis, Hui-Ping Lin, Shih Sheng Jiang, Ching-Yu Lin, Junichi Fukuchi, Richard A. Hiipakka, Chi-Jung Chung, Tzu-Min Chan, Shutsung Liao, Chung-Ho Chang, Chih-Pin Chuu

published 01 Oct 2014

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Resveratrol Modulates Cytokine-Induced JAK/STAT Activation More Efficiently than 5-Aminosalicylic Acid: An In Vitro Approach

Diana Serra, Ana T. Rufino, Alexandrina F. Mendes, Leonor M. Almeida, Teresa C. P. Dinis

published 01 Oct 2014

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The Indolinone MAZ51 Induces Cell Rounding and G2/M Cell Cycle Arrest in Glioma Cells without the Inhibition of VEGFR-3 Phosphorylation: Involvement of the RhoA and Akt/GSK3β Signaling Pathways

Joo-Hee Park, Yoo-Jin Shin, Tae-Ryong Riew, Mun-Yong Lee

published 30 Sep 2014

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