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Post-translational modification

Suprafenacine, an Indazole-Hydrazide Agent, Targets Cancer Cells Through Microtubule Destabilization

Bo-Hwa Choi, Souvik Chattopadhaya, Le Nguyen Thanh, Lin Feng, Quoc Toan Nguyen, Chuan Bian Lim, Amaravadhi Harikishore, Ravi Prakash Reddy Nanga, Nagakumar Bharatham, Yan Zhao, Xuewei Liu, Ho Sup Yoon

published 29 Oct 2014

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The Functions of Crucial Cysteine Residues in the Arsenite Methylation Catalyzed by Recombinant Human Arsenic (III) Methyltransferase

Shuping Wang, Zhirong Geng, Nan Shi, Xiangli Li, Zhilin Wang

published 28 Oct 2014

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Extracellular Regulation of Sperm Transmembrane Adenylyl Cyclase by a Forward Motility Stimulating Protein

Souvik Dey, Debarun Roy, Gopal C. Majumder, Debdas Bhattacharyya

published 28 Oct 2014

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Neuronal Differentiation Dictates Estrogen-Dependent Survival and ERK1/2 Kinetic by Means of Caveolin-1

Floriana Volpicelli, Massimiliano Caiazzo, Bruno Moncharmont, Umberto di Porzio, Luca Colucci-D’Amato

published 28 Oct 2014

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Src Mutation Induces Acquired Lapatinib Resistance in ERBB2-Amplified Human Gastroesophageal Adenocarcinoma Models

Yong Sang Hong, Jihun Kim, Eirini Pectasides, Cameron Fox, Seung-Woo Hong, Qiuping Ma, Gabrielle S. Wong, Shouyong Peng, Matthew D. Stachler, Aaron R. Thorner, Paul Van Hummelen, Adam J. Bass

published 28 Oct 2014

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Epitope Tags beside the N-Terminal Cytoplasmic Tail of Human BST-2 Alter Its Intracellular Trafficking and HIV-1 Restriction

Mingyu Lv, Jiawen Wang, Jingyao Zhang, Biao Zhang, Xiaodan Wang, Yingzi Zhu, Tao Zuo, Donglai Liu, Xiaojun Li, Jiaxin Wu, Haihong Zhang, Bin Yu, Hui Wu, Xinghong Zhao, Wei Kong, Xianghui Yu

published 27 Oct 2014

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The HBx Oncoprotein of Hepatitis B Virus Deregulates the Cell Cycle by Promoting the Intracellular Accumulation and Re-Compartmentalization of the Cellular Deubiquitinase USP37

Nehul Saxena, Vijay Kumar

published 27 Oct 2014

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Activin B Antagonizes RhoA Signaling to Stimulate Mesenchymal Morphology and Invasiveness of Clear Cell Renal Cell Carcinomas

Ingrid Wacker, Jürgen Behrens

published 24 Oct 2014

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DDX3X Induces Primary EGFR-TKI Resistance Based on Intratumor Heterogeneity in Lung Cancer Cells Harboring EGFR-Activating Mutations

Koichiro Nozaki, Hiroshi Kagamu, Satoshi Shoji, Natsue Igarashi, Aya Ohtsubo, Masaaki Okajima, Satoru Miura, Satoshi Watanabe, Hirohisa Yoshizawa, Ichiei Narita

published 24 Oct 2014

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The Mre11-Rad50-Xrs2 Complex Is Required for Yeast DNA Postreplication Repair

Lindsay G. Ball, Michelle D. Hanna, Amanda D. Lambrecht, Bryan A. Mitchell, Barry Ziola, Jennifer A. Cobb, Wei Xiao

published 24 Oct 2014

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TMEM43 Mutation p.S358L Alters Intercalated Disc Protein Expression and Reduces Conduction Velocity in Arrhythmogenic Right Ventricular Cardiomyopathy

Vinayakumar Siragam, Xuezhi Cui, Stephane Masse, Cameron Ackerley, Shabana Aafaqi, Linn Strandberg, Michael Tropak, Michael D. Fridman, Kumaraswamy Nanthakumar, Jun Liu, Yu Sun, Bin Su, Caroline Wang, Xiaoru Liu, Yuqing Yan, Ariel Mendlowitz, Robert M. Hamilton

published 24 Oct 2014

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The Inhibition of N-Glycosylation of Glycoprotein 130 Molecule Abolishes STAT3 Activation by IL-6 Family Cytokines in Cultured Cardiac Myocytes

Reo Matsuo, Hirofumi Morihara, Tomomi Mohri, Shiho Murasawa, Kana Takewaki, Hiroyuki Nakayama, Makiko Maeda, Yasushi Fujio

published 23 Oct 2014

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Phosphorylation of HPV-16 E2 at Serine 243 Enables Binding to Brd4 and Mitotic Chromosomes

Szu-Wei Chang, Wei-Chen Liu, Kuan-Yu Liao, Yeou-Ping Tsao, Pang-Hung Hsu, Show-Li Chen

published 23 Oct 2014

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