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Post-translational modification

Novel Bruton’s tyrosine kinase inhibitor TAS5315 suppresses the progression of inflammation and joint destruction in rodent collagen-induced arthritis

Daichi Akasaka, Satoru Iguchi, [ ... ], Fumihito Hosoi

Merlin tumor suppressor function is regulated by PIP₂-mediated dimerization

Robert F. Hennigan, Craig S. Thomson, [ ... ], Nancy Ratner

Metformin regulates myoblast differentiation through an AMPK-dependent mechanism

Eleonora Maniscalco, Giuliana Abbadessa, [ ... ], Silvia Racca

Suppression of angiotensin converting enzyme 2, a host receptor for SARS-CoV-2 infection, using 5-aminolevulinic acid in vitro

Eriko Nara, Hung Wei Lai, [ ... ], Shun-Ichiro Ogura

Mutation of regulatory phosphorylation sites in PFKFB2 does not affect the anti-fibrotic effect of metformin in the kidney

Geoff Harley, Marina Katerelos, [ ... ], David A. Power

Electrophysiological evaluation of an anticancer drug gemcitabine on cardiotoxicity revealing down-regulation and modification of the activation gating properties in the human rapid delayed rectifier potassium channel

Mengyan Wei, Pu Wang, [ ... ], Katsushige Ono

The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells

Nadine Bachtler, Sandra Torres, [ ... ], Sabine Klein

Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration

Shreyasi Chatterjee, Megan Sealey, [ ... ], Amritpal Mudher

The Q163C/Q309C mutant of α_MI-domain is an active variant suitable for NMR characterization

Hoa Nguyen, Tianwei Jing, Xu Wang

Stability analysis of a multiscale model of cell cycle dynamics coupled with quiescent and proliferating cell populations

Iqra Batool, Naim Bajcinca

Farnesol and phosphorylation of the transcriptional regulator Efg1 affect Candida albicans white-opaque switching rates

Lucas R. Brenes, Alexander D. Johnson, Matthew B. Lohse

Tramadol regulates the activation of human platelets via Rac but not Rho/Rho-kinase

Hiroki Iida, Takashi Onuma, [ ... ], Haruhiko Tokuda

SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework

Mehreen Gul, Ahmad Navid, Muhammad Fakhar, Sajid Rashid

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