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Post-translational modification

ALK Kinase Domain Mutations in Primary Anaplastic Large Cell Lymphoma: Consequences on NPM-ALK Activity and Sensitivity to Tyrosine Kinase Inhibitors

Federica Lovisa, Giorgio Cozza, Andrea Cristiani, Alberto Cuzzolin, Alessandro Albiero, Lara Mussolin, Marta Pillon, Stefano Moro, Giuseppe Basso, Angelo Rosolen, Paolo Bonvini

published 13 Apr 2015

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The Ubiquitination of the Influenza A Virus PB1-F2 Protein Is Crucial for Its Biological Function

Ivan Košík, Margaréta Práznovská, Martina Košíková, Zuzana Bobišová, Jaroslav Hollý, Eva Varečková, František Kostolanský, Gustáv Russ

published 13 Apr 2015

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Characterization of the Loss of SUMO Pathway Function on Cancer Cells and Tumor Proliferation

Xingyue He, Jessica Riceberg, Sai M. Pulukuri, Steve Grossman, Vaishali Shinde, Pooja Shah, James E. Brownell, Larry Dick, John Newcomb, Neil Bence

published 10 Apr 2015

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ING5 Is Phosphorylated by CDK2 and Controls Cell Proliferation Independently of p53

Ulrike Linzen, Richard Lilischkis, Ruwin Pandithage, Britta Schilling, Andrea Ullius, Juliane Lüscher-Firzlaff, Elisabeth Kremmer, Bernhard Lüscher, Jörg Vervoorts

published 10 Apr 2015

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Biochemical Analysis of the NAD⁺-Dependent Malate Dehydrogenase, a Substrate of Several Serine/Threonine Protein Kinases of Mycobacterium tuberculosis

Xiao Ming Wang, Karine Soetaert, Priska Peirs, Michaël Kalai, Véronique Fontaine, Jean Paul Dehaye, Philippe Lefèvre

published 10 Apr 2015

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The GTPase-Activating Protein Rga1 Interacts with Rho3 GTPase and May Regulate Its Function in Polarized Growth in Budding Yeast

Fei He, Wen-Chao Nie, Zongtian Tong, Si-Min Yuan, Ting Gong, Yuan Liao, Erfei Bi, Xiang-Dong Gao

published 10 Apr 2015

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Melanocortins Contribute to Sequential Differentiation and Enucleation of Human Erythroblasts via Melanocortin Receptors 1, 2 and 5

Eriko Simamura, Tomohiro Arikawa, Takayuki Ikeda, Hiroki Shimada, Hiroki Shoji, Hiroko Masuta, Yuriko Nakajima, Hiroki Otani, Hideto Yonekura, Toshihisa Hatta

published 10 Apr 2015

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aPKC Phosphorylation of HDAC6 Results in Increased Deacetylation Activity

Yifeng Du, Michael L. Seibenhener, Jin Yan, Jianxiong Jiang, Michael C. Wooten

published 10 Apr 2015

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Filamin-A Increases the Stability and Plasma Membrane Expression of Polycystin-2

Qian Wang, Wang Zheng, Zuocheng Wang, JungWoo Yang, Shaimaa Hussein, Jingfeng Tang, Xing-Zhen Chen

published 10 Apr 2015

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tRNA^Glu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications

Sébastien P. Blais, Jack A. Kornblatt, Xavier Barbeau, Guillaume Bonnaure, Patrick Lagüe, Robert Chênevert, Jacques Lapointe

published 10 Apr 2015

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α-Actinin-4 Enhances Colorectal Cancer Cell Invasion by Suppressing Focal Adhesion Maturation

Miki Fukumoto, Shusaku Kurisu, Tesshi Yamada, Tadaomi Takenawa

published 10 Apr 2015

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Direct Binding of Ledipasvir to HCV NS5A: Mechanism of Resistance to an HCV Antiviral Agent

Hyock Joo Kwon, Weimei Xing, Katie Chan, Anita Niedziela-Majka, Katherine M. Brendza, Thorsten Kirschberg, Darryl Kato, John O. Link, Guofeng Cheng, Xiaohong Liu, Roman Sakowicz

published 09 Apr 2015

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Small Peptide Inhibitor of JNK3 Protects Dopaminergic Neurons from MPTP Induced Injury via Inhibiting the ASK1-JNK3 Signaling Pathway

Jing Pan, Hui Li, Bei Zhang, Ran Xiong, Yu Zhang, Wen-Yan Kang, Wei Chen, Zong-Bo Zhao, Sheng-Di Chen

published 09 Apr 2015

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