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Post-translational modification

Elucidating the isorhamnetin-3-O-glucoside-iNOS interaction via molecular dynamics and Hirshfeld surface analyses

Oussama Khibech, Haytham Bouammali, Yousra Hammouti, Mohamed bouhrim, Mohammed Merzouki, Said Abadi, Mohammed Al-zharani, Fahd A. Nasr, Ashraf Ahmed Qurtam, Boufelja Bouammalli, Allal Challioui

published 19 Dec 2025

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Far-infrared irradiation attenuates vessel contraction by activating SERCA2 through disruption of SERCA2 and PLN interaction

Yun-Jin Hwang, So-Young Park, Jung-Hyun Park, Du-Hyong Cho

published 17 Dec 2025

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Identification and validation of palmitoylation-related signature genes based on machine learning for prostate cancer

Qijun Wo, Jiafeng Shou, Jun Shi, Lei Shi, YunKai Yang, Yifan Wang, Liping Xie

published 04 Dec 2025

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Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility

Martina Ramella, Daniele Brambilla, Sara Surini, Diletta Tonoli, Lucrezia Maria Ribolla, Ivan de Curtis

published 01 Dec 2025

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TNFAIP3 alleviates cerebral ischemia-reperfusion injury by inhibiting M1 microglia polarization via deubiquitination of RACK1

Wenya Bai, Shixuan Liu, Guilin Zhou, Xuelian Li, Huan Jiang, Jianlin Shao, Junchao Zhu

published 26 Nov 2025

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Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats

Caroline Gatwiri Gitonga, Charles Githinji, Boniface Chege, Frederick Bukachi, Peter Waweru

published 26 Nov 2025

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Warburg-Cinotti disease variant p.Tyr740Cys enhances catalytic activity of DDR2 kinase

Ziteng Hao, Birgit Leitinger

published 19 Nov 2025

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Using machine learning for detection of Parkinson’s disease and mild cognitive impairment

Anthaea-Grace Patricia Dennis, Sarah L. Martin, Robert Chen, Philip Gerretsen, Antonio P. Strafella

published 19 Nov 2025

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In silico structural analysis of Oryza sativa RAD51 reveals key interactions for nucleoprotein filament assembly and regulation

Ayesha Azeem, Syed Farhat Ali, Rana Salman Anjum

published 12 Nov 2025

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Design of a multi-epitope recombinant BCG vaccine targeting Brucella OMP31, LptE and VirB2 in immunoinformatics approaches

Chuang Li, Yuejie Zhu, Xingxing Qi, Zhenglong Chai, Jiarui Luo, Kaiyu Shang, Tingting Tian, Huidong Shi, Mingzhe Li, Ruixue Xu, Fuling Pu, Junyu Kuang, Fengbo Zhang

published 06 Nov 2025

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Impact of histone post-translational modification inhibitors on lifespan, reproduction, and stress response in the rotifer Brachionus manjavacas

Nelia Luviano Aparicio, Meghan Dryburgh, Colleen M. McMaken, Alyssa Liguori, Kristin E. Gribble

published 29 Oct 2025

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TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models

Lai Jiang, Yue Jin, Yujia Han, Jin Fu

published 24 Oct 2025

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Mixed twitch and tetanus electrical stimulation via belt-electrode effectively attenuates denervation-induced muscle atrophy

Hiroyuki Uno, Mako Isemura, Shohei Kamiya, Ryuji Akimoto, Katsu Hosoki, Shunta Tadano, Karina Kouzaki, Yuki Tamura, Takaya Kotani, Koichi Nakazato

published 15 Oct 2025

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