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Post-translational modification

SUMO-dependent transcriptional repression by Sox2 inhibits the proliferation of neural stem cells

Elisa Marelli, Jaime Hughes, Paul J. Scotting

published 20 Mar 2024

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Substrate preference of protein kinase B isoforms can vary depending on the cell line

Miguel S. Palma, Samantha R. Perez, Aida Husain, Deepali Bhandari

published 19 Mar 2024

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Equilibrium landscape of ingress/egress channels and gating residues of the Cytochrome P450 3A4

Edward Michael Ackad, Laurence Biggers, Mary Meister, Maria Kontoyianni

published 18 Mar 2024

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The N-linked glycosylation modifications in the hepatitis B surface protein impact cellular autophagy, HBV replication, and HBV secretion

Patcharin Tepjanta, Kazuhito Fujiyama, Ryo Misaki, Ingorn Kimkong

published 15 Mar 2024

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The polyglutamine domain is the primary driver of seeding in huntingtin aggregation

Adam Skeens, Chathuranga Siriwardhana, Sophia E. Massinople, Michelle M. Wunder, Zachary L. Ellis, Kaitlyn M. Keith, Tyler Girman, Shelli L. Frey, Justin Legleiter

published 14 Mar 2024

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Characterization of intestinal O-glycome in reactive oxygen species deficiency

Radka Saldova, Kristina A. Thomsson, Hayden Wilkinson, Maitrayee Chatterjee, Ashish K. Singh, Niclas G. Karlsson, Ulla G. Knaus

published 14 Mar 2024

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Autocrine phosphatase PDP2 inhibits ferroptosis by dephosphorylating ACSL4 in the Luminal A Breast Cancer

Jun-Jie Zhu, Feng-Ying Huang, Hengyu Chen, Yun-long Zhang, Ming-Hui Chen, Ri-Hong Wu, Shu-Zhen Dai, Gui-Sheng He, Guang-Hong Tan, Wu-Ping Zheng

published 11 Mar 2024

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Autophagy and oxidative stress modulation mediate Bortezomib resistance in prostate cancer

Kalliopi Zafeiropoulou, Georgios Kalampounias, Spyridon Alexis, Daniil Anastasopoulos, Argiris Symeonidis, Panagiotis Katsoris

published 27 Feb 2024

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, the Emory-Sage-SGC TREAT-AD Center , Alison D. Axtman

published 15 Feb 2024

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Discovery and characterization of anti-cancer peptides from a random peptide library

Pavan Kumar Puvvula, Anne M. Moon

published 13 Feb 2024

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Poly-(ADP-ribose) polymerases inhibition by olaparib attenuates activities of the NLRP3 inflammasome and of NF-κB in THP-1 monocytes

Khamis Mustafa, Ying Han, Dan He, Ying Wang, Nan Niu, Pedro A. Jose, Yinong Jiang, Jeffrey B. Kopp, Hewang Lee, Peng Qu

published 09 Feb 2024

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Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis

Bonnie A. Thiel, Kathleen C. Lundberg, Daniela Schlatzer, Jessica Jarvela, Qing Li, Rachel Shaw, Scott M. Reba, Shane Fletcher, Sara E. Beckloff, Mark R. Chance, W. Henry Boom, Richard F. Silver, Gurkan Bebek

published 01 Feb 2024

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Src-NADH dehydrogenase subunit 2 complex and recognition memory of imprinting in domestic chicks

Lela Chitadze, Maia Meparishvili, Vincenzo Lagani, Zaza Khuchua, Brian J. McCabe, Revaz Solomonia

published 29 Jan 2024

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