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Post-translational modification

AviTrap: A novel solution to achieve complete biotinylation

Cheng Lu, Jack Bevers, Tulika Tyagi, Hao To, May Lin, Shu Ti, Gerry Nakamura, WeiYu Lin, Yongmei Chen, Yan Wu, Hong Li, Jiansheng Wu, Feng Wang

published 25 Apr 2024

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Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43

Paula Castellanos Otero, Tiffany W. Todd, Wei Shao, Caroline J. Jones, Kexin Huang, Lillian M. Daughrity, Mei Yue, Udit Sheth, Tania F. Gendron, Mercedes Prudencio, Björn Oskarsson, Dennis W. Dickson, Leonard Petrucelli, Yong-Jie Zhang

published 18 Apr 2024

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Protective role of protease-activated receptor-2 in anaphylaxis model mice

Maho Nakazawa, Ryota Tochinai, Wataru Fujii, Mao Komori, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda

published 18 Apr 2024

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Lineage-specific gene duplication and expansion of DUF1216 gene family in Brassicaceae

Zai-Bao Zhang, Tao Xiong, Xiao-Jia Wang, Yu-Rui Chen, Jing-Lei Wang, Cong-Li Guo, Zi-Yi Ye

published 16 Apr 2024

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Bioinformatics-driven discovery of novel EGFR kinase inhibitors as anti-cancer therapeutics: In silico screening and in vitro evaluation

Awwad A. Radwan, Fars Alanazi, Abdullah Al-Dhfyan

published 16 Apr 2024

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Searching for new plastic-degrading enzymes from the plastisphere of alpine soils using a metagenomic mining approach

Beat Frey, Margherita Aiesi, Basil M. Rast, Joel Rüthi, Jérôme Julmi, Beat Stierli, Weihong Qi, Ivano Brunner

published 05 Apr 2024

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Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform

Lijuan Zhou, Fei Cai, Yanjie Li, Xinxin Gao, Yuehua Wei, Anna Fedorova, Daniel Kirchhofer, Rami N. Hannoush, Yingnan Zhang

published 28 Mar 2024

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A phage-displayed disulfide constrained peptide discovery platform yields novel human plasma protein binders

Xinxin Gao, Harini Kaluarachchi, Yingnan Zhang, Sunhee Hwang, Rami N. Hannoush

published 28 Mar 2024

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HMGR and CHS gene cloning, characterizations and tissue-specific expressions in Polygala tenuifolia Willd

Yang Liu, Xiaofang Ma, Fuying Mao, Jinmiao Qiu, Jingyi Bi, Xiaowei Li, Xian Gu, Yuguang Zheng, Yunsheng Zhao

published 25 Mar 2024

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Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro

Keishi Shintomi, Yuki Masahara-Negishi, Masami Shima, Shoji Tane, Tatsuya Hirano

published 25 Mar 2024

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Targeted degradation of zDHHC-PATs decreases substrate S-palmitoylation

Mingjie Bai, Emily Gallen, Sarah Memarzadeh, Jacqueline Howie, Xing Gao, Chien-Wen S. Kuo, Elaine Brown, Simon Swingler, Sam J. Wilson, Michael J. Shattock, David J. France, William Fuller

published 21 Mar 2024

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SUMO-dependent transcriptional repression by Sox2 inhibits the proliferation of neural stem cells

Elisa Marelli, Jaime Hughes, Paul J. Scotting

published 20 Mar 2024

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Substrate preference of protein kinase B isoforms can vary depending on the cell line

Miguel S. Palma, Samantha R. Perez, Aida Husain, Deepali Bhandari

published 19 Mar 2024

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