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Post-translational modification

The IKK Inhibitor Bay 11-7082 Induces Cell Death Independent from Inhibition of Activation of NFκB Transcription Factors

Hilka Rauert-Wunderlich, Daniela Siegmund, [ ... ], Thorsten Stühmer

Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

Tao Ma, Charles A. Hoeffer, [ ... ], Gunnar K. Gouras

Stabilisation of the Fc Fragment of Human IgG1 by Engineered Intradomain Disulfide Bonds

Gordana Wozniak-Knopp, Johannes Stadlmann, Florian Rüker

STAT3 Is Activated by JAK2 Independent of Key Oncogenic Driver Mutations in Non-Small Cell Lung Carcinoma

Brendan D. Looyenga, Danielle Hutchings, [ ... ], Jeffrey P. MacKeigan

The IkappaB Kinase Family Phosphorylates the Parkinson’s Disease Kinase LRRK2 at Ser935 and Ser910 during Toll-Like Receptor Signaling

Nicolas Dzamko, Francisco Inesta-Vaquera, [ ... ], Dario R. Alessi

Sickle Erythrocytes Target Cytotoxics to Hypoxic Tumor Microvessels and Potentiate a Tumoricidal Response

David S. Terman, Benjamin L. Viglianti, [ ... ], Mark W. Dewhirst

Phosphorylation of Drebrin by Cyclin-Dependent Kinase 5 and Its Role in Neuronal Migration

Kazuya Tanabe, Hiroyuki Yamazaki, [ ... ], Shin-ichi Hisanaga

A Phos-Tag-Based Approach Reveals the Extent of Physiological Endoplasmic Reticulum Stress

Liu Yang, Zhen Xue, [ ... ], Ling Qi

3.5Å cryoEM Structure of Hepatitis B Virus Core Assembled from Full-Length Core Protein

Xuekui Yu, Lei Jin, [ ... ], Z. Hong Zhou

The Arabidopsis ABA-Activated Kinase OST1 Phosphorylates the bZIP Transcription Factor ABF3 and Creates a 14-3-3 Binding Site Involved in Its Turnover

Caroline Sirichandra, Marlène Davanture, [ ... ], Sylvain Merlot

Lycopene Inhibits NF-kB-Mediated IL-8 Expression and Changes Redox and PPARγ Signalling in Cigarette Smoke–Stimulated Macrophages

Rossella E. Simone, Marco Russo, [ ... ], Paola Palozza

SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity

Jin Yan, Michael Lamar Seibenhener, [ ... ], Michael C. Wooten

The Acid Test of Fluoride: How pH Modulates Toxicity

Ramaswamy Sharma, Masahiro Tsuchiya, [ ... ], John D. Bartlett

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