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Post-translational modification

Multivalency drives interactions of alpha-synuclein fibrils with tau

Jennifer Ramirez, Ibrahim G. Saleh, Evan S. K. Yanagawa, Marie Shimogawa, Emily Brackhahn, E. James Petersson, Elizabeth Rhoades

published 10 Sep 2024

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Strategies found not to be suitable for stabilizing high steroid hydroxylation activities of CYP450 BM3-based whole-cell biocatalysts

Carolin Bertelmann, Bruno Bühler

published 06 Sep 2024

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Development of innovative multi-epitope mRNA vaccine against central nervous system tuberculosis using in silico approaches

Huidong Shi, Yuejie Zhu, Kaiyu Shang, Tingting Tian, Zhengwei Yin, Juan Shi, Yueyue He, Jianbing Ding, Quan Wang, Fengbo Zhang

published 06 Sep 2024

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PIK-III exerts anti-fibrotic effects in activated fibroblasts by regulating p38 activation

Santiago Sanchez, Aaron K. McDowell-Sanchez, Sharaz B. Al-Meerani, Juan D. Cala-Garcia, Alan R. Waich Cohen, Scott A. Ochsner, Neil J. McKenna, Lindsay J. Celada, Minghua Wu, Shervin Assassi, Ivan O. Rosas, Konstantin Tsoyi

published 06 Sep 2024

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Feasibility of the inhibitor development for cancer: A systematic approach for drug design

Yu Jiang, Ling Liu, Yichao Geng, Qingsong Li, Daxian Luo, Li Liang, Wei Liu, Weiwei Ouyang, Jianping Hu

published 22 Aug 2024

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KIC (ketoisocaproic acid) and leucine have divergent effects on tissue insulin signaling but not on whole-body insulin sensitivity in rats

Gagandeep Mann, Stephen Mora, Olasunkanmi A. John Adegoke

published 20 Aug 2024

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Remote liver ischemic preconditioning protects against renal ischemia/reperfusion injury via phosphorylation of extracellular signal-regulated kinases 1 and 2 in mice

Qifeng Wang, Junshen Xiao, Shichao Wei, Xi Yang, Jiaxue Li, Yunxia Zuo, Zhaoyang Hu

published 19 Aug 2024

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Atorvastatin inhibits Lipopolysaccharide (LPS)-induced vascular inflammation to protect endothelium by inducing Heme Oxygenase-1 (HO-1) expression

Jian Luo, Qian Zhu, Keming Huang, Xue Wen, Yongquan Peng, Gong Chen, Gang Wei

published 15 Aug 2024

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The role of palbociclib on the alterations in CDKN2, CCNE1, E2F3, MDM2 expressions as target genes of miR-141

Mohammad Ali Baziyar, Arshad Hosseini, Farinush Jandel

published 08 Aug 2024

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A new type II CHH neuropeptide involves ovarian development in the peppermint shrimp, Lysmata vittata

Huiling Lan, Fang Liu, Li Lu, An Liu, Haihui Ye

published 01 Aug 2024

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Synergistic effect of PAK and Hippo pathway inhibitor combination in NF2-deficient Schwannoma

Dorothy Benton, Hoi Yee Chow, Sofiia Karchugina, Jonathan Chernoff

published 31 Jul 2024

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Zbtb11 interacts with Otx2 and patterns the anterior neuroectoderm in Xenopus

Yumeko Satou-Kobayashi, Shuji Takahashi, Yoshikazu Haramoto, Makoto Asashima, Masanori Taira

published 31 Jul 2024

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USP26 suppresses type I interferon signaling by targeting TRAF3 for deubiquitination

Cheng-Lan Sheng, Bang-Dong Jiang, Chun-Qiu Zhang, Jin-Hua Huang, Zi Wang, Chao Xu

published 26 Jul 2024

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