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Post-translational modification

Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase

Sean J. Ezekiel, Mackenzie Searle, Jaeok Park

published 15 Jan 2025

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Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways

Binmei Zhang, Jingxiu Hou, Jiaren Liu, Junhui He, Yunan Gao, Guangnan Li, Tianjiao Ma, Xin Lv, Li Dong, Wei Yang

published 08 Jan 2025

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In vitro and in silico analyses of amino acid substitution effects at the conserved N-linked glycosylation site in hepatitis B virus surface protein on antigenicity, immunogenicity, HBV replication and secretion

Patcharin Tepjanta, Thammakorn Saethang, Kazuhito Fujiyama, Ryo Misaki, Ingorn Kimkong

published 06 Jan 2025

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High glucose couples DJ-1 with PTEN to activate PDGFRβ for renal proximal tubular cell injury

Falguni Das, Nandini Ghosh-Choudhury, Balakuntalam S. Kasinath, Kumar Sharma, Goutam Ghosh Choudhury

published 06 Jan 2025

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Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation

Michael O. Isei, Meredith Crockett, Emily Chen, Joel Rodwell-Bullock, Trae Carroll, Peter A. Girardi, Keith Nehrke, Gail V. W. Johnson

published 03 Jan 2025

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Site-specific prediction of O-GlcNAc modification in proteins using evolutionary scale model

Ayesha Khalid, Afshan Kaleem, Wajahat Qazi, Roheena Abdullah, Mehwish Iqtedar, Shagufta Naz

published 31 Dec 2024

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Identification of O-glycosylation related genes and subtypes in ulcerative colitis based on machine learning

Yue Lu, Yi Su, Nan Wang, Dongyue Li, Huichao Zhang, Hongyu Xu

published 31 Dec 2024

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Oscillatory autophagy induction is enabled by an updated AMPK-ULK1 regulatory wiring

Orsolya Kapuy, Marianna Holczer, Luca Csabai, Tamás Korcsmáros

published 26 Dec 2024

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Accelerating antimicrobial peptide design: Leveraging deep learning for rapid discovery

Ahmad M. Al-Omari, Yazan H. Akkam, Ala’a Zyout, Shayma’a Younis, Shefa M. Tawalbeh, Khaled Al-Sawalmeh, Amjed Al Fahoum, Jonathan Arnold

published 20 Dec 2024

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Sodium butyrate is incorporated into central metabolism in fly head while inducing oxygen consumption increase

Annika Müller-Eigner, Benedikt Gille, Frederik Dethloff, Chen Meng, Christina Ludwig, John T. Heiker, Patrick Giavalisco, Shahaf Peleg

published 19 Dec 2024

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Characterization of a novel subfamily 1.4 lipase from Bacillus licheniformis IBRL-CHS2: Cloning and expression optimization

Ammar Khazaal Kadhim Almansoori, Nidyaletchmy Subba Reddy, Mustafa Abdulfattah, Sarah Solehah Ismail, Rashidah Abdul Rahim

published 17 Dec 2024

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Identifying immune cell infiltration and effective diagnostic biomarkers for ischemic stroke using bioinformatics analysis

Zongyong Zhang, Zongqing Zheng, Wenwei Luo, Jiebo Li, Jiushan Liao, Fuxiang Chen, Dengliang Wang, Yuanxiang Lin

published 05 Dec 2024

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Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis

Albrecht Meyer zu Schwabedissen, Silvia Vergarajauregui, Marko Bertog, Kerstin Amann, Felix B. Engel, Christoph Daniel

published 05 Dec 2024

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