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Point mutation

Rosetta:MSF:NN: Boosting performance of multi-state computational protein design with a neural network

Julian Nazet, Elmar Lang, Rainer Merkl

published 26 Aug 2021

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SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts

Rafail Nikolaos Tasakis, Georgios Samaras, Anna Jamison, Michelle Lee, Alexandra Paulus, Gabrielle Whitehouse, Laurent Verkoczy, F. Nina Papavasiliou, Marilyn Diaz

published 23 Jul 2021

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The interplay of Rac1 activity, ubiquitination and GDI binding and its consequences for endothelial cell spreading

Jisca Majolée, Fabienne Podieh, Peter L. Hordijk, Igor Kovačević

published 12 Jul 2021

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High-throughput sequencing reveals genetic determinants associated with antibiotic resistance in Campylobacter spp. from farm-to-fork

Shaimaa F. Mouftah, José F. Cobo-Díaz, Avelino Álvarez-Ordóñez, Menattallah Elserafy, Nehal A. Saif, Asmaa Sadat, Ayman El-Shibiny, Mohamed Elhadidy

published 24 Jun 2021

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Resistance mechanisms and fitness of pyraclostrobin-resistant isolates of Lasiodiplodia theobromae from mango orchards

Rui He, Ye Yang, Zhizhong Hu, Ru Xue, Yajuan Hu

published 23 Jun 2021

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Sperm parameters and mitochondrial DNA sequence variants among patients at a fertility clinic in Ghana

Bartholomew Dzudzor, Bismarck Bimah, Vincent Amarh, Augustine Ocloo

published 15 Jun 2021

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In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function

Liza Teresa Rozario, Tanima Sharker, Tasnin Akter Nila

published 14 Jun 2021

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Rapid detection of multidrug-resistant tuberculosis based on allele-specific recombinase polymerase amplification and colorimetric detection

Nuntita Singpanomchai, Yukihiro Akeda, Kazunori Tomono, Aki Tamaru, Pitak Santanirand, Panan Ratthawongjirakul

published 11 Jun 2021

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Selective transport of fluorescent proteins into the phage nucleus

Katrina T. Nguyen, Joseph Sugie, Kanika Khanna, MacKennon E. Egan, Erica A. Birkholz, Jina Lee, Christopher Beierschmitt, Elizabeth Villa, Joe Pogliano

published 10 Jun 2021

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Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model

Nicole K. Polinski, Terina N. Martinez, Alexander Gorodinsky, Ralph Gareus, Michael Sasner, Mark Herberth, Robert Switzer, Syed O. Ahmad, Mali Cosden, Monika Kandebo, Robert E. Drolet, Peter D. Buckett, Weisong Shan, Yi Chen, Lee J. Pellegrino, Gregory D. Ellsworth, Leo B. Dungan, Warren D. Hirst, Sean W. Clark, Kuldip D. Dave

published 09 Jun 2021

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Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants’ spike protein–an in silico analysis

Suman Pokhrel, Benjamin R. Kraemer, Lucia Lee, Kate Samardzic, Daria Mochly-Rosen

published 26 May 2021

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Structure-activity mapping of ARHGAP36 reveals regulatory roles for its GAP homology and C-terminal domains

Patricia R. Nano, Taylor K. Johnson, Takamasa Kudo, Nancie A. Mooney, Jun Ni, Janos Demeter, Peter K. Jackson, James K. Chen

published 17 May 2021

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Prevalence of colorectal cancer biomarkers and their impact on clinical outcomes in Riyadh, Saudi Arabia

Amjad Alharbi, Haifa Bin Dokhi, Ghadir Almuhaini, Futoon Alomran, Emad Masuadi, Nouf Alomran

published 12 May 2021

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