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Phosphorylation

Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43

Paula Castellanos Otero, Tiffany W. Todd, Wei Shao, Caroline J. Jones, Kexin Huang, Lillian M. Daughrity, Mei Yue, Udit Sheth, Tania F. Gendron, Mercedes Prudencio, Björn Oskarsson, Dennis W. Dickson, Leonard Petrucelli, Yong-Jie Zhang

published 18 Apr 2024

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Protective role of protease-activated receptor-2 in anaphylaxis model mice

Maho Nakazawa, Ryota Tochinai, Wataru Fujii, Mao Komori, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda

published 18 Apr 2024

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Bioinformatics-driven discovery of novel EGFR kinase inhibitors as anti-cancer therapeutics: In silico screening and in vitro evaluation

Awwad A. Radwan, Fars Alanazi, Abdullah Al-Dhfyan

published 16 Apr 2024

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Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro

Keishi Shintomi, Yuki Masahara-Negishi, Masami Shima, Shoji Tane, Tatsuya Hirano

published 25 Mar 2024

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Substrate preference of protein kinase B isoforms can vary depending on the cell line

Miguel S. Palma, Samantha R. Perez, Aida Husain, Deepali Bhandari

published 19 Mar 2024

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Autocrine phosphatase PDP2 inhibits ferroptosis by dephosphorylating ACSL4 in the Luminal A Breast Cancer

Jun-Jie Zhu, Feng-Ying Huang, Hengyu Chen, Yun-long Zhang, Ming-Hui Chen, Ri-Hong Wu, Shu-Zhen Dai, Gui-Sheng He, Guang-Hong Tan, Wu-Ping Zheng

published 11 Mar 2024

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Autophagy and oxidative stress modulation mediate Bortezomib resistance in prostate cancer

Kalliopi Zafeiropoulou, Georgios Kalampounias, Spyridon Alexis, Daniil Anastasopoulos, Argiris Symeonidis, Panagiotis Katsoris

published 27 Feb 2024

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, the Emory-Sage-SGC TREAT-AD Center , Alison D. Axtman

published 15 Feb 2024

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Poly-(ADP-ribose) polymerases inhibition by olaparib attenuates activities of the NLRP3 inflammasome and of NF-κB in THP-1 monocytes

Khamis Mustafa, Ying Han, Dan He, Ying Wang, Nan Niu, Pedro A. Jose, Yinong Jiang, Jeffrey B. Kopp, Hewang Lee, Peng Qu

published 09 Feb 2024

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Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis

Bonnie A. Thiel, Kathleen C. Lundberg, Daniela Schlatzer, Jessica Jarvela, Qing Li, Rachel Shaw, Scott M. Reba, Shane Fletcher, Sara E. Beckloff, Mark R. Chance, W. Henry Boom, Richard F. Silver, Gurkan Bebek

published 01 Feb 2024

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Src-NADH dehydrogenase subunit 2 complex and recognition memory of imprinting in domestic chicks

Lela Chitadze, Maia Meparishvili, Vincenzo Lagani, Zaza Khuchua, Brian J. McCabe, Revaz Solomonia

published 29 Jan 2024

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Methods optimization for the expression and purification of human calcium calmodulin-dependent protein kinase II alpha

Scott C. Bolton, David H. Thompson, Tamara L. Kinzer-Ursem

published 05 Jan 2024

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Proliferation, migration and phenotypic transformation of VSMC induced via Hcy related to up-expression of WWP2 and p-STAT3

Xiuyu Wang, Na Gui, Xing Ma, Yue Zeng, Tingrun Mo, Minghao Zhang

published 02 Jan 2024

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