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Phosphorylation

SRC-1 controls growth cone polarity and protrusion with the UNC-6/Netrin receptor UNC-5 in Caenorhabditis elegans

Snehal S. Mahadik, Emily K. Burt, Erik A. Lundquist

published 21 May 2024

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Fusion of histone variants to Cas9 suppresses non-homologous end joining

Tomoko Kato-Inui, Gou Takahashi, Terumi Ono, Yuichiro Miyaoka

published 13 May 2024

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Mexenone protects mice from LPS-induced sepsis by EC barrier stabilization

Yoon Ji Choi, Jimin An, Ji Hye Kim, Sa Bin Lee, Bo Seok Lee, Chae Young Eom, Hyohi Lee, Nayeong Kwon, Il Shin Kim, Kyoung-Su Park, Sooah Park, Jung-Woog Shin, Sanguk Yun

published 09 May 2024

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Poly(A)-binding protein promotes VPg-dependent translation of potyvirus through enhanced binding of phosphorylated eIFiso4F and eIFiso4F∙eIF4B

Mateen A. Khan, Sumeyra Yumak, Hiroshi Miyoshi

published 02 May 2024

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Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43

Paula Castellanos Otero, Tiffany W. Todd, Wei Shao, Caroline J. Jones, Kexin Huang, Lillian M. Daughrity, Mei Yue, Udit Sheth, Tania F. Gendron, Mercedes Prudencio, Björn Oskarsson, Dennis W. Dickson, Leonard Petrucelli, Yong-Jie Zhang

published 18 Apr 2024

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Protective role of protease-activated receptor-2 in anaphylaxis model mice

Maho Nakazawa, Ryota Tochinai, Wataru Fujii, Mao Komori, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda

published 18 Apr 2024

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Bioinformatics-driven discovery of novel EGFR kinase inhibitors as anti-cancer therapeutics: In silico screening and in vitro evaluation

Awwad A. Radwan, Fars Alanazi, Abdullah Al-Dhfyan

published 16 Apr 2024

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Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro

Keishi Shintomi, Yuki Masahara-Negishi, Masami Shima, Shoji Tane, Tatsuya Hirano

published 25 Mar 2024

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Substrate preference of protein kinase B isoforms can vary depending on the cell line

Miguel S. Palma, Samantha R. Perez, Aida Husain, Deepali Bhandari

published 19 Mar 2024

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Autocrine phosphatase PDP2 inhibits ferroptosis by dephosphorylating ACSL4 in the Luminal A Breast Cancer

Jun-Jie Zhu, Feng-Ying Huang, Hengyu Chen, Yun-long Zhang, Ming-Hui Chen, Ri-Hong Wu, Shu-Zhen Dai, Gui-Sheng He, Guang-Hong Tan, Wu-Ping Zheng

published 11 Mar 2024

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Autophagy and oxidative stress modulation mediate Bortezomib resistance in prostate cancer

Kalliopi Zafeiropoulou, Georgios Kalampounias, Spyridon Alexis, Daniil Anastasopoulos, Argiris Symeonidis, Panagiotis Katsoris

published 27 Feb 2024

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, the Emory-Sage-SGC TREAT-AD Center , Alison D. Axtman

published 15 Feb 2024

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Poly-(ADP-ribose) polymerases inhibition by olaparib attenuates activities of the NLRP3 inflammasome and of NF-κB in THP-1 monocytes

Khamis Mustafa, Ying Han, Dan He, Ying Wang, Nan Niu, Pedro A. Jose, Yinong Jiang, Jeffrey B. Kopp, Hewang Lee, Peng Qu

published 09 Feb 2024

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