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Phosphorylation

Network pharmacology combined with experimental validation show that apigenin as the active ingredient of Campsis grandiflora flower against Parkinson’s disease by inhibiting the PI3K/AKT/NF-κB pathway

Kai Liu, Jing An, [ ... ], Zhaohui He

Hederagenin regulates the migration and invasion of hepatocellular carcinoma cells through FOXO signaling pathway

Shuchang Bao, Songzhe Li, Yang Sun

Role of canonical and non-canonical cAMP sources in CRHR2α-dependent signaling

Natalia G. Armando, Paula A. dos Santos Claro, [ ... ], Susana Silberstein

Signal-sensing triggers the shutdown of HemKR, regulating heme and iron metabolism in the spirochete Leptospira biflexa

Juan Andrés Imelio, Felipe Trajtenberg, [ ... ], Alejandro Buschiazzo

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

Kelly Lim, Winnie L. Kan, [ ... ], Daniel Thomas

Multivalency drives interactions of alpha-synuclein fibrils with tau

Jennifer Ramirez, Ibrahim G. Saleh, [ ... ], Elizabeth Rhoades

Feasibility of the inhibitor development for cancer: A systematic approach for drug design

Yu Jiang, Ling Liu, [ ... ], Jianping Hu

KIC (ketoisocaproic acid) and leucine have divergent effects on tissue insulin signaling but not on whole-body insulin sensitivity in rats

Gagandeep Mann, Stephen Mora, Olasunkanmi A. John Adegoke

Remote liver ischemic preconditioning protects against renal ischemia/reperfusion injury via phosphorylation of extracellular signal-regulated kinases 1 and 2 in mice

Qifeng Wang, Junshen Xiao, [ ... ], Zhaoyang Hu

The role of palbociclib on the alterations in CDKN2, CCNE1, E2F3, MDM2 expressions as target genes of miR-141

Mohammad Ali Baziyar, Arshad Hosseini, Farinush Jandel

Zbtb11 interacts with Otx2 and patterns the anterior neuroectoderm in Xenopus

Yumeko Satou-Kobayashi, Shuji Takahashi, [ ... ], Masanori Taira

Radioprotective effect of the anti-diabetic drug metformin

Silvia Siteni, Summer Barron, Krishna Luitel, Jerry W. Shay

Dual-targeting class I HDAC inhibitor and ATM activator, SP-1-303, preferentially inhibits estrogen receptor positive breast cancer cell growth

Mira Jung, Nicole Nicholas, Scott Grindrod, Anatoly Dritschilo

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