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Phosphorylation

High glucose couples DJ-1 with PTEN to activate PDGFRβ for renal proximal tubular cell injury

Falguni Das, Nandini Ghosh-Choudhury, Balakuntalam S. Kasinath, Kumar Sharma, Goutam Ghosh Choudhury

published 06 Jan 2025

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Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation

Michael O. Isei, Meredith Crockett, Emily Chen, Joel Rodwell-Bullock, Trae Carroll, Peter A. Girardi, Keith Nehrke, Gail V. W. Johnson

published 03 Jan 2025

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Oscillatory autophagy induction is enabled by an updated AMPK-ULK1 regulatory wiring

Orsolya Kapuy, Marianna Holczer, Luca Csabai, Tamás Korcsmáros

published 26 Dec 2024

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Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis

Albrecht Meyer zu Schwabedissen, Silvia Vergarajauregui, Marko Bertog, Kerstin Amann, Felix B. Engel, Christoph Daniel

published 05 Dec 2024

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Ruscus aculeatus extract promotes RNase 7 expression through ERK activation following inhibition of late-phase autophagy in primary human keratinocytes

Shigeyuki Ono, Akiko Kawasaki, Kotaro Tamura, Yoshihiko Minegishi, Takuya Mori, Noriyasu Ota

published 03 Dec 2024

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Identification and validation of ATP6V1G1-regulated phosphorylated proteins in hepatocellular carcinoma

Yi Zhang, Liuyi Lu, Mingxing Chen, Jiaqi Nie, Xue Qin, Huaping Chen

published 02 Dec 2024

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Pine pollen reverses the function of hepatocellular carcinoma by inhibiting α-Enolase mediated PI3K/AKT signaling pathway

Yanhong Luo, Chun Guo, Caixia Ling, Wenjun Yu, Yuanhong Chen, Lihe Jiang, Qiuxiang Luo, Chunfang Wang, Weixin Xu

published 22 Nov 2024

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PTEN depletion reduces H3K27me3 levels to promote epithelial-to-mesenchymal transition in epithelial colorectal cancer cells

Ahmed H. Ghobashi, Jane W. Kimani, Christopher A. Ladaika, Heather M. O’Hagan

published 19 Nov 2024

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Stem cell factor restrains endoplasmic reticulum stress-associated apoptosis through c-Kit receptor activation of JAK2/STAT3 axis in hippocampal neuronal cells

Haiying Shen, Junjie Nie, Guangqing Li, Hongyan Tian, Jun Zhang, Xiaofeng Luo, Da Xu, Jie Sun, Dongfang Zhang, Hong Zhang, Guifang Zhao, Weiyao Wang, Zhonghua Zheng, Shuyan Yang, Yuji Jin

published 15 Nov 2024

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Characterizing the role of PP2A B’’ family subunits in mechanical stress response and plant development through calcium and ABA signaling in Arabidopsis thaliana

Hyuk Sung Yoon, Kaien Fujino, Shenkui Liu, Tetsuo Takano, Daisuke Tsugama

published 14 Nov 2024

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Palmitoyl-L-carnitine induces tau phosphorylation and mitochondrial dysfunction in neuronal cells

Gwangho Yoon, Min Kyoung Kam, Young Ho Koh, Chulman Jo

published 13 Nov 2024

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Ca²⁺-PP2B-PSD-95 axis: A novel regulatory mechanism of the phosphorylation state of Serine 295 of PSD-95

Takahiko Chimura, Toshiya Manabe

published 07 Nov 2024

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SARS-CoV-2 propagation to the TPH2-positive neurons in the ventral tegmental area induces cell death via GSK3β-dependent accumulation of phosphorylated tau

Motoki Imai, Fumitaka Kawakami, Takayuki Uematsu, Toshihide Matsumoto, Rei Kawashima, Yoshifumi Kurosaki, Shun Tamaki, Shotaro Maehana, Takafumi Ichikawa, Hideaki Hanaki, Hidero Kitazato, Makoto Kubo

published 30 Oct 2024

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