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Phosphorylation

Proteomic and phosphoproteomic analysis of rabies pathogenesis in the clinical canine brain and identification of a kinase inhibitor as a potential repurposed antiviral agent

Peerut Chienwichai, Kunjimas Ketsuwan, Boonlert Lumlertdacha, Chanon Fa-Ngoen, Punchaya Supasawat, Rojjanaporn Pulmanausahakul, Promsin Masrinoul, Tipparat Thiangtrongjit, Onrapak Reamtong

published 27 Jun 2025

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Prostaglandin E₂ dependent migration of human brain endothelial cells is mediated through Rho-Kinase-II

Gausal Azam Khan, Arjun Ghosh

published 23 Jun 2025

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Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure

Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Yasumasa Mototani, Megumi Nariyama, Aiko Ito, Ichiro Matsuo, Yoshio Hayakawa, Akinaka Morii, Takao Mitsubayashi, Yasutake Saeki, Yoshihiro Ishikawa, Satoshi Okumura

published 17 Jun 2025

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JAK inhibitor withdrawal causes a transient pro-inflammatory cascade: A potential mechanism for major adverse cardiac events

Ilya Gurevic, Loic Meudec, Xavier Mariette, Gaetane Nocturne, Sara S. McCoy

published 16 Jun 2025

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Anti-β₂GPI/β₂GPI complex promotes thrombosis by activating the P2Y₂/MAPKs pathway to increase human neutrophil peptides

Xin Guan, Wen Liu, Tianfeng Gao, Wenying Jin, Yueqiu Gao, Huiyuan Tan, Lujie Guo, Yanfen Zhang

published 22 May 2025

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Mechanistic studies of PFKFB2 reveal a novel inhibitor of its kinase activity

Craig Eyster, Satoshi Matsuzaki, Atul Pranay, Jennifer R. Giorgione, Anna Faakye, Mostafa Ahmed, Kenneth M. Humphries

published 22 May 2025

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Rottlerin inhibits macropinocytosis of Porcine Reproductive and Respiratory Syndrome Virus through the PKCδ-Cofilin signaling pathway

Yeonglim Kang, Jong-Chul Choi, Joong-Bok Lee, Seung-Yong Park, Changin Oh

published 20 May 2025

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Epidemiological investigation and analysis of the genetic evolution of duck circovirus in China, 2022

Peidong Li, Fuyou Zhang, Chunyang Bao, Hongmei Liu, Kai Yu, Hao Zhu, Xue Wang, Ke Shen, Tianyao Yang, Qingqing Song, Zhaoyang Li, Chunguo Liu

published 09 May 2025

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The ubiquitin-like modifier FAT10 does not affect IL-12 expression and signaling

Jinjing Cao, Gerardo Omar Alvarez Salinas, Gunter Schmidtke, Michael Basler

published 06 May 2025

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PTPN21 inhibits cell apoptosis of acute lymphoblastic leukemia induced by chemotherapeutic agents via GADD45A and JNK signaling pathway

Chenze Zhao, Yu Zhang, Linlin Huang, Jingjing Xiang, Baodong Ye, Ni Zhu

published 30 Apr 2025

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Expression and immunological role of FUNDC2 in pan-cancer

Xirong Qiu, Shuyu Wang, Chenlu Li, Yinan Wang

published 28 Apr 2025

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Human cytomegalovirus infection induces L1 expression through UL38-dependent mTOR-KAP1 pathway

Sehong Park, Jiseok Jeong, Kwangseog Ahn

published 23 Apr 2025

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Allopurinol attenuates development of Porphyromonas gingivalis LPS-induced cardiomyopathy in mice

Akinaka Morii, Ichiro Matsuo, Kenji Suita, Yoshiki Ohnuki, Misao Ishikawa, Aiko Ito, Go Miyamoto, Mariko Abe, Takao Mitsubayashi, Yasumasa Mototani, Megumi Nariyama, Ren Matsubara, Yoshio Hayakawa, Yasuharu Amitani, Kazuhiro Gomi, Takatoshi Nagano, Satoshi Okumura

published 03 Apr 2025

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