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Phosphorylation

DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling

Xiaochen Tian, Jing Li, Tao Han, Leisheng Zhang, Ping Lu, Yusheng Liu

published 17 Apr 2026

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Human resistin is critical to activation of the NLRP3 inflammasome in macrophages

Udeshika Kariyawasam, Winson Lam, John Skinner, Rituparna Chakrabarti, Andrea Cox, Paul M. Hassoun, Qing Lin, Roger A. Johns

published 10 Apr 2026

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Identification of neuronatin as a SERCA2b regulin-like protein and assessment of its aggregation propensity via coarse grained simulations

Omar Ben Mariem, Lara Coppi, Emma De Fabiani, Ivano Eberini, Maurizio Crestani

published 09 Apr 2026

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Myc and Skp2 overexpression promotes p27 ubiquitination and degradation in Ewing Sarcoma

Yuta Kubota, Masanori Kawano, Ichiro Itonaga, Nobuhiro Kaku, Kazuhiro Tanaka

published 09 Mar 2026

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Phosphorylations of serines 21/9 in glycogen synthase kinase 3α/β are dispensable for ^V600EBRAF-driven premalignant tumour development in the mouse intestine

Pooyeh Farahmand, Paulina Rzasa, Caleb Green, Fiona Hey, Susan Giblett, Hong Jin, Kevin West, Nicolas B. Sylvius, Catrin A. Pritchard, Alessandro Rufini

published 06 Mar 2026

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Characterization of the TREM-1 signaling landscape in human neutrophils

Frederic Ries, Matthias Klein, Nora Rogmann, Sophie Többen, Federico Marini, Florian Heidel, Markus P. Radsak

published 05 Mar 2026

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Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype

Xuerao Ning, Thảo Thi Thanh Nguyễn, Takao Morinaga, Yuji Tada, Hideaki Shimada, Kenzo Hiroshima, Naoto Yamaguchi, Masatoshi Tagawa

published 23 Feb 2026

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TL1A serves as a positive regulator to promote adipocyte differentiation

Ziqi Chang, Qiaoyu Wang, Yan Zhai, Ke Li, Xianjie Zheng, Yaohui Wang, Dan Zhao

published 19 Feb 2026

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The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat model

Lin Yang, Jie He

published 17 Feb 2026

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Reducing OGT and O-GlcNAcylation enhance the anticancer effects of oxaliplatin in SW620 metastatic colorectal cancer cells

Thirasak Bunsuk, Juthamard Chantaraamporn, Photsathorn Mutapat, Penchatr Diskul Na Ayudthaya, Daranee Chokchaichamnankit, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai

published 10 Feb 2026

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Quantitative and temporal analysis of autophagy: Differential Response to amino acid and glucose starvation

Katie R. Martin, Stephanie L. Celano, Jessica D. Guillaume, Ryan D. Sheldon, Russell G. Jones, Jeffrey P. MacKeigan

published 04 Feb 2026

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Enarodustat suppresses thymic stromal lymphopoietin expression via hypoxia-inducible factor-mediated c-Jun N-terminal kinases dephosphorylation

Ryosuke Segawa, Makiko Yagisawa, Chihiro Miyata, Noriyasu Hirasawa

published 23 Jan 2026

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Pharmacokinetics of Dolutegravir, nucleoside analogues, and intracellular metabolites using plasma separation cards: A comparative analysis with traditional sampling methods in healthy volunteers

Beth Thompson, Laura J. Else, Laura Dickinson, Stacey Edick, Ashley Zyhowski, Ken Ho, Leslie Meyn, Sujan Dilly-Penchala, Victoria Shaw, Ian McGowan, Saye Khoo, Rhonda M. Brand

published 23 Jan 2026

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