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Phosphorothioates

Cleavage of MALAT1 RNA by 14-nt sgRNA-guided tRNase Z^L

Masayuki Takahashi, Masayuki Nashimoto

published 18 Sep 2025

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Developing predictive hybridization models for phosphorothioate oligonucleotides using high-resolution melting

Siyuan S. Wang, Erhu Xiong, Sanchita Bhadra, Andrew D. Ellington

published 18 May 2022

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Refining LNA safety profile by controlling phosphorothioate stereochemistry

Erik Daa Funder, Nanna Albæk, Annie Moisan, Sabine Sewing, Troels Koch

published 12 Jun 2020

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Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production

Christopher S. Malarkey, Claire E. Gustafson, Jessica F. Saifee, Raul M. Torres, Mair E. A. Churchill, Edward N. Janoff

published 09 Jun 2016

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Antiplatelet Activity, P2Y₁ and P2Y₁₂ Inhibition, and Metabolism in Plasma of Stereoisomers of Diadenosine 5′,5′″-P¹,P⁴-dithio-P²,P³-chloromethylenetetraphosphate

Hung Chang, Ivan B. Yanachkov, Edward J. Dix, Milka Yanachkova, YouFu Li, Marc R. Barnard, George E. Wright, Alan D. Michelson, Andrew L. Frelinger III

published 10 Apr 2014

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Enzymatic Cleavage of Type II Restriction Endonucleases on the 2′-O-Methyl Nucleotide and Phosphorothioate Substituted DNA

Guojie Zhao, Jun Li, Zhaoxue Tong, Bin Zhao, Runqing Mu, Yifu Guan

published 15 Nov 2013

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Combinatorial Engineering of 1-Deoxy-D-Xylulose 5-Phosphate Pathway Using Cross-Lapping In Vitro Assembly (CLIVA) Method

Ruiyang Zou, Kang Zhou, Gregory Stephanopoulos, Heng Phon Too

published 05 Nov 2013

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Effective Exon Skipping and Dystrophin Restoration by 2′-O-Methoxyethyl Antisense Oligonucleotide in Dystrophin-Deficient Mice

Lu Yang, Hongjing Niu, Xianjun Gao, Qingsong Wang, Gang Han, Limin Cao, Chunquan Cai, Jan Weiler, Haifang Yin

published 26 Apr 2013

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Improving Lambda Red Genome Engineering in Escherichia coli via Rational Removal of Endogenous Nucleases

Joshua A. Mosberg, Christopher J. Gregg, Marc J. Lajoie, Harris H. Wang, George M. Church

published 05 Sep 2012

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Transformation with Oligonucleotides Creating Clustered Changes in the Yeast Genome

Gina P. Rodriguez, Joseph B. Song, Gray F. Crouse

published 14 Aug 2012

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Characterization of Family IV UDG from Aeropyrum pernix and Its Application in Hot-Start PCR by Family B DNA Polymerase

Xi-Peng Liu, Jian-Hua Liu

published 08 Nov 2011

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