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Pharmacokinetics

Contribution of Cytochrome P450 and ABCB1 Genetic Variability on Methadone Pharmacokinetics, Dose Requirements, and Response

Francina Fonseca, Rafael de la Torre, [ ... ], Marta Torrens

A Soluble Acetylcholinesterase Provides Chemical Defense against Xenobiotics in the Pinewood Nematode

Jae Soon Kang, Dae-Weon Lee, Young Ho Koh, Si Hyeock Lee

Disease-Related Changes in the Cerebrospinal Fluid Metabolome in Amyotrophic Lateral Sclerosis Detected by GC/TOFMS

Anna Wuolikainen, Thomas Moritz, [ ... ], Peter Munch Andersen

Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory

Binu Shrestha, J. Michael Reed, [ ... ], Michael H. Court

A New Method for Morphometric Analysis of Tissue Distribution of Mobile Cells in Relation to Immobile Tissue Structures

Liudmila Nikitina, Helmut Ahammer, [ ... ], Peter Sedlmayr

An Effective Assessment of Simvastatin-Induced Toxicity with NMR-Based Metabonomics Approach

Hye-ji Yang, Myung-Joo Choi, [ ... ], Sunghyouk Park

Enhanced Uridine Bioavailability Following Administration of a Triacetyluridine-Rich Nutritional Supplement

Melissa E. Weinberg, Mark C. Roman, [ ... ], Morris Schambelan

Newly Identified CYP2C93 Is a Functional Enzyme in Rhesus Monkey, but Not in Cynomolgus Monkey

Yasuhiro Uno, Shotaro Uehara, [ ... ], Hiroshi Yamazaki

Functional Magnetic Resonance Imaging Reveals Different Neural Substrates for the Effects of Orexin-1 and Orexin-2 Receptor Antagonists

Alessandro Gozzi, Giuliano Turrini, [ ... ], Angelo Bifone

Improving Cancer Classification Accuracy Using Gene Pairs

Pankaj Chopra, Jinseung Lee, Jaewoo Kang, Sunwon Lee

Metabolic Activity and mRNA Levels of Human Cardiac CYP450s Involved in Drug Metabolism

Veronique Michaud, Martin Frappier, Marie-Christine Dumas, Jacques Turgeon

Metabolomic Profiling of Cellular Responses to Carvedilol Enantiomers in Vascular Smooth Muscle Cells

Mingxuan Wang, Jing Bai, Wei Ning Chen, Chi Bun Ching

Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting

Karsten Suhre, Christa Meisinger, [ ... ], Thomas Illig

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