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Phagosomes

Arp2/3 complex contributes to the actin-dependent uptake of Aspergillus terreus conidia by alveolar epithelial cells

Natalia Mach, Julien Polleux, Lea Heinrich, Lukas Lechner, Iryna Levytska, Cornelia Lass-Flörl, Susanne Perkhofer

published 28 Jan 2026

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Role of mTORC1 signaling in postnatal microglia activation preceding neurodegeneration in a mouse model for Niemann-Pick disease Type C

Caroline E. Murray, David S. Betancourt-Trompa, Michael S. Martinez, Julia M. Carson, Lindsay J. Walsh, Will C. Remillard, Kayla B. Fordyce, Rohan Reddy, Ileana Soto

published 05 Sep 2025

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ECDD-S16, a synthetic derivative of cleistanthin A, suppresses pyroptosis in Burkholderia pseudomallei-infected U937 macrophages

Suphasuta Khongpraphan, Sucharat Sanongkiet, Chularat Luangjindarat, Sarut Thairat, Bumrung Munyoo, Napason Chabang, Sitthivut Charoensutthivarakul, Suparerk Borwornpinyo, Patoomratana Tuchinda, Marisa Ponpuak, Pongsak Utaisincharoen, Matsayapan Pudla

published 08 Jul 2025

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Phagolysosomes break down the membrane of a non-apoptotic corpse independent of macroautophagy

Shruti Kolli, Cassidy J. Kline, Kimya M. Rad, Ann M. Wehman

published 21 Nov 2024

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Compound K14 inhibits bacterial killing and protease activity in Dictyostelium discoideum phagosomes

Estelle Ifrid, Hajer Ouertatani-Sakouhi, Hiba Zein El Dine, Tania Jauslin, Gianpaolo Chiriano, Leonardo Scapozza, Otmane Lamrabet, Pierre Cosson

published 26 Aug 2024

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Gold Particle Analyser: Detection and quantitative assessment of electron microscopy gold probes

Thomas Burgoyne, Clare E. Futter

published 28 Jul 2023

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Vomocytosis of Cryptococcus neoformans cells from murine, bone marrow-derived dendritic cells

Noah Pacifici, Melissa Cruz-Acuña, Agustina Diener, Allen Tu, Neeraj Senthil, Hyunsoo Han, Jamal S. Lewis

published 16 Mar 2023

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Deficiency in Lyst function leads to accumulation of secreted proteases and reduced retinal adhesion

Xiaojie Ji, Lihong Zhao, Ankita Umapathy, Bernard Fitzmaurice, Jieping Wang, David S. Williams, Bo Chang, Jürgen K. Naggert, Patsy M. Nishina

published 03 Mar 2022

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Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation

Sam C. Nalle, Rosa Barreira da Silva, Hua Zhang, Markus Decker, Cecile Chalouni, Min Xu, George Posthuma, Ann de Mazière, Judith Klumperman, Adriana Baz Morelli, Sebastian J. Fleire, Alan S. Verkman, E. Sergio Trombetta, Matthew L. Albert, Ira Mellman

published 24 Nov 2020

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Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage

Morwan M. Osman, Antonio J. Pagán, Jonathan K. Shanahan, Lalita Ramakrishnan

published 23 Jul 2020

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The pattern recognition receptors dectin-2, mincle, and FcRγ impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species

Mohammed Haider, Ivy M. Dambuza, Patawee Asamaphan, Mark Stappers, Delyth Reid, Sho Yamasaki, Gordon D. Brown, Neil A. R. Gow, Lars P. Erwig

published 08 Aug 2019

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Hydroalcoholic extract from Origanum vulgare induces a combined anti-mycobacterial and anti-inflammatory response in innate immune cells

Federica De Santis, Noemi Poerio, Angelo Gismondi, Valentina Nanni, Gabriele Di Marco, Roberto Nisini, Maria Cristina Thaller, Antonella Canini, Maurizio Fraziano

published 04 Mar 2019

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The cAMP effectors, Rap2b and EPAC, are involved in the regulation of the development of the Coxiella burnetii containing vacuole by altering the fusogenic capacity of the vacuole

María Eugenia Mansilla Pareja, Maria Celeste Gaurón, Esteban Robledo, Milton Osmar Aguilera, María Isabel Colombo

published 14 Feb 2019

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