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Partial agonists

Identification of Distant Drug Off-Targets by Direct Superposition of Binding Pocket Surfaces

Marcel Schumann, Roger S. Armen

published 31 Dec 2013

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Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors

Barbara G. Campling, Alexander Kuryatov, Jon Lindstrom

published 14 Nov 2013

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Impact of Polymorphic Variants on the Molecular Pharmacology of the Two-Agonist Conformations of the Human β1-Adrenoceptor

Jillian G. Baker, Richard G. W. Proudman, Stephen J. Hill

published 08 Nov 2013

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Effect of Iboga Alkaloids on µ-Opioid Receptor-Coupled G Protein Activation

Tamara Antonio, Steven R. Childers, Richard B. Rothman, Christina M. Dersch, Christine King, Martin Kuehne, William G. Bornmann, Amy J. Eshleman, Aaron Janowsky, Eric R. Simon, Maarten E. A. Reith, Kenneth Alper

published 16 Oct 2013

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Partial Agonism of Taurine at Gamma-Containing Native and Recombinant GABA_A Receptors

Olaf Kletke, Guenter Gisselmann, Andrea May, Hanns Hatt, Olga A. Sergeeva

published 30 Apr 2013

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Polyacetylenes from Notopterygium incisum–New Selective Partial Agonists of Peroxisome Proliferator-Activated Receptor-Gamma

Atanas G. Atanasov, Martina Blunder, Nanang Fakhrudin, Xin Liu, Stefan M. Noha, Clemens Malainer, Matthias P. Kramer, Amina Cocic, Olaf Kunert, Andreas Schinkovitz, Elke H. Heiss, Daniela Schuster, Verena M. Dirsch, Rudolf Bauer

published 22 Apr 2013

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Full and Partial Agonists of Thromboxane Prostanoid Receptor Unveil Fine Tuning of Receptor Superactive Conformation and G Protein Activation

Valérie Capra, Marta Busnelli, Alessandro Perenna, Manuela Ambrosio, Maria Rosa Accomazzo, Celine Galés, Bice Chini, G. Enrico Rovati

published 28 Mar 2013

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Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors

Tino Wolter, Thomas Steinbrecher, Marcus Elstner

published 25 Mar 2013

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Identification of PPARgamma Partial Agonists of Natural Origin (II): In Silico Prediction in Natural Extracts with Known Antidiabetic Activity

Laura Guasch, Esther Sala, Miquel Mulero, Cristina Valls, Maria Josepa Salvadó, Gerard Pujadas, Santiago Garcia-Vallvé

published 06 Feb 2013

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Stimulation of Inositol 1,4,5-Trisphosphate (IP₃) Receptor Subtypes by Analogues of IP₃

Huma Saleem, Stephen C. Tovey, Taufiq Rahman, Andrew M. Riley, Barry V. L. Potter, Colin W. Taylor

published 25 Jan 2013

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Neurogenic and Neurotrophic Effects of BDNF Peptides in Mouse Hippocampal Primary Neuronal Cell Cultures

Maria del Carmen Cardenas-Aguayo, Syed Faraz Kazim, Inge Grundke-Iqbal, Khalid Iqbal

published 08 Jan 2013

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Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and In Vitro Validation

Laura Guasch, Esther Sala, Anna Castell-Auví, Lidia Cedó, Klaus R. Liedl, Gerhard Wolber, Markus Muehlbacher, Miquel Mulero, Montserrat Pinent, Anna Ardévol, Cristina Valls, Gerard Pujadas, Santiago Garcia-Vallvé

published 30 Nov 2012

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Allosteric Modulation of the Activity of the Glucagon-like Peptide-1 (GLP-1) Metabolite GLP-1 9–36 Amide at the GLP-1 Receptor

Naichang Li, Jing Lu, Gary B. Willars

published 19 Oct 2012

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