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Partial agonists

5-HT₂ receptor binding, functional activity and selectivity in N-benzyltryptamines

Miguel Toro-Sazo, José Brea, [ ... ], Bruce K. Cassels

Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders

Bitna Yi, Alam Jahangir, [ ... ], Mehrdad Shamloo

Active-State Model of a Dopamine D₂ Receptor - Gα_i Complex Stabilized by Aripiprazole-Type Partial Agonists

Ralf C. Kling, Nuska Tschammer, [ ... ], Peter Gmeiner

Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors

Tino Wolter, Thomas Steinbrecher, Marcus Elstner

Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2

D. Malfacini, C. Ambrosio, [ ... ], G. Calo’

Extending the Applicability of the Dose Addition Model to the Assessment of Chemical Mixtures of Partial Agonists by Using a Novel Toxic Unit Extrapolation Method

Martin Scholze, Elisabete Silva, Andreas Kortenkamp

Stimulation of Inositol 1,4,5-Trisphosphate (IP₃) Receptor Subtypes by Analogues of IP₃

Huma Saleem, Stephen C. Tovey, [ ... ], Colin W. Taylor

Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors

Barbara G. Campling, Alexander Kuryatov, Jon Lindstrom

Structural Mechanism of N-Methyl-D-Aspartate Receptor Type 1 Partial Agonism

Mikko Ylilauri, Olli T. Pentikäinen

Label-Free Phenotypic Profiling Identified D-Luciferin as a GPR35 Agonist

Haibei Hu, Huayun Deng, Ye Fang

An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist

Eswarkumar Nadendla, Catherine Teyssier, [ ... ], Pierre Germain

Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists

Katrine Qvortrup, Jakob F. Jensen, [ ... ], Thomas E. Nielsen

The Extracellular Loop 2 (ECL2) of the Human Histamine H₄ Receptor Substantially Contributes to Ligand Binding and Constitutive Activity

David Wifling, Günther Bernhardt, Stefan Dove, Armin Buschauer

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