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Oncolytic viruses

Neutralizing monoclonal antibodies improve biodistribution of intravenously administered oncolytic adenovirus in human CD46-transgenic mice

Masahisa Hemmi, Midori Yamashita, Yoshiko Shimizu, Shinsuke Nakao

published 25 Jun 2025

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Transcriptome insights into newcastle disease virus-mediated eradication of cholangiocarcinoma cells

Suphannee Thanyaphoo, Chanachai Sae-Lee, Wilasinee Thaopech, Warisa Amornrit, Mutita Junking, Pa-thai Yenchitsomanus, Naravat Poungvarin

published 06 May 2025

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Mathematical modelling of reoviruses in cancer cell cultures

Arwa Abdulla Baabdulla, Francisca Cristi, Maya Shmulevitz, Thomas Hillen

published 28 Apr 2025

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A novel oncolytic vaccinia virus with multiple gene modifications involved in viral replication and maturation increases safety for intravenous administration while maintaining proliferative potential in cancer cells

Go Okita, Kiyotaka Suenaga, Masashi Sakaguchi, Toshio Murakami

published 06 Mar 2025

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p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells

Shuta Tamura, Hiroshi Tazawa, Naoto Hori, Yuncheng Li, Motohiko Yamada, Satoru Kikuchi, Shinji Kuroda, Yasuo Urata, Shunsuke Kagawa, Toshiyoshi Fujiwara

published 16 Nov 2023

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The chicken chorioallantoic membrane model for isolation of CRISPR/cas9-based HSV-1 mutant expressing tumor suppressor p53

Mishar Kelishadi, Hosein Shahsavarani, Alijan Tabarraei, Mohammad Ali Shokrgozar, Ladan Teimoori-Toolabi, Kayhan Azadmanesh

published 20 Oct 2023

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Optimizing environmental safety and cell-killing potential of oncolytic Newcastle Disease virus with modifications of the V, F and HN genes

J. Fréderique de Graaf, Stefan van Nieuwkoop, Theo Bestebroer, Daphne Groeneveld, Casper H. J. van Eijck, Ron A. M. Fouchier, Bernadette G. van den Hoogen

published 09 Feb 2022

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Real-time monitoring of oncolytic VSV properties in a novel in vitro microphysiological system containing 3D multicellular tumor spheroids

Kyoung Jin Lee, Sang Woo Lee, Ha-Na Woo, Hae Mi Cho, Dae Bong Yu, Soo Yeon Jeong, Chul Hyun Joo, Gi Seok Jeong, Heuiran Lee

published 06 Jul 2020

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Zika virus as an oncolytic treatment of human neuroblastoma cells requires CD24

Joseph Mazar, Yujia Li, Amy Rosado, Peter Phelan, Kritika Kedarinath, Griffith D. Parks, Kenneth A. Alexander, Tamarah J. Westmoreland

published 25 Jul 2018

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Oncolytic potency and reduced virus tumor-specificity in oncolytic virotherapy. A mathematical modelling approach

Khaphetsi Joseph Mahasa, Amina Eladdadi, Lisette de Pillis, Rachid Ouifki

published 21 Sep 2017

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Cytokine-induced killer cell delivery enhances the antitumor activity of oncolytic reovirus

Xing Zhao, Weiwei Ouyang, Cariad Chester, Shiqi Long, Nianxue Wang, Zhixu He

published 18 Sep 2017

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Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes

Nalini Marino, Sam Illingworth, Prithvi Kodialbail, Ashvin Patel, Hugo Calderon, Rochelle Lear, Kerry D. Fisher, Brian R. Champion, Alice C. N. Brown

published 18 May 2017

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IRF1 Downregulation by Ras/MEK Is Independent of Translational Control of IRF1 mRNA

Yumiko Komatsu, Leena Derwish, Kensuke Hirasawa

published 10 Aug 2016

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