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Next-generation sequencing

Clinical Validation of an Ultra High-Throughput Spiral Microfluidics for the Detection and Enrichment of Viable Circulating Tumor Cells

Bee Luan Khoo, Majid Ebrahimi Warkiani, Daniel Shao-Weng Tan, Ali Asgar S. Bhagat, Darryl Irwin, Dawn Pingxi Lau, Alvin S. T. Lim, Kiat Hon Lim, Sai Sakktee Krisna, Wan-Teck Lim, Yoon Sim Yap, Soo Chin Lee, Ross A. Soo, Jongyoon Han, Chwee Teck Lim

published 07 Jul 2014

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Single-Step Selection of Bivalent Aptamers Validated by Comparison with SELEX Using High-Throughput Sequencing

Robert Wilson, Christian Bourne, Roy R. Chaudhuri, Richard Gregory, John Kenny, Andrew Cossins

published 25 Jun 2014

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Whole Genome and Exome Sequencing of Monozygotic Twins with Trisomy 21, Discordant for a Congenital Heart Defect and Epilepsy

Pongsathorn Chaiyasap, Supasak Kulawonganunchai, Chalurmpon Srichomthong, Sissades Tongsima, Kanya Suphapeetiporn, Vorasuk Shotelersuk

published 20 Jun 2014

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Targeted Next-Generation Sequencing at Copy-Number Breakpoints for Personalized Analysis of Rearranged Ends in Solid Tumors

Hyun-Kyoung Kim, Won Cheol Park, Kwang Man Lee, Hai-Li Hwang, Seong-Yeol Park, Sungbin Sorn, Vishal Chandra, Kwang Gi Kim, Woong-Bae Yoon, Joon Seol Bae, Hyoung Doo Shin, Jong-Yeon Shin, Ju-Young Seoh, Jong-Il Kim, Kyeong-Man Hong

published 17 Jun 2014

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Construction and Analysis of High-Density Linkage Map Using High-Throughput Sequencing Data

Dongyuan Liu, Chouxian Ma, Weiguo Hong, Long Huang, Min Liu, Hui Liu, Huaping Zeng, Dejing Deng, Huaigen Xin, Jun Song, Chunhua Xu, Xiaowen Sun, Xilin Hou, Xiaowu Wang, Hongkun Zheng

published 06 Jun 2014

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CloudDOE: A User-Friendly Tool for Deploying Hadoop Clouds and Analyzing High-Throughput Sequencing Data with MapReduce

Wei-Chun Chung, Chien-Chih Chen, Jan-Ming Ho, Chung-Yen Lin, Wen-Lian Hsu, Yu-Chun Wang, D. T. Lee, Feipei Lai, Chih-Wei Huang, Yu-Jung Chang

published 04 Jun 2014

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High Throughput Mutagenesis for Identification of Residues Regulating Human Prostacyclin (hIP) Receptor Expression and Function

Anke Bill, Elizabeth M. Rosethorne, Toby C. Kent, Lindsay Fawcett, Lynn Burchell, Michiel T. van Diepen, Anthony Marelli, Sergey Batalov, Loren Miraglia, Anthony P. Orth, Nicole A. Renaud, Steven J. Charlton, Martin Gosling, L. Alex Gaither, Paul J. Groot-Kormelink

published 02 Jun 2014

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Bacterial Diversity Assessment in Antarctic Terrestrial and Aquatic Microbial Mats: A Comparison between Bidirectional Pyrosequencing and Cultivation

Bjorn Tytgat, Elie Verleyen, Dagmar Obbels, Karolien Peeters, Aaike De Wever, Sofie D’hondt, Tim De Meyer, Wim Van Criekinge, Wim Vyverman, Anne Willems

published 02 Jun 2014

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The Validation and Clinical Implementation of BRCAplus: A Comprehensive High-Risk Breast Cancer Diagnostic Assay

Hansook Kim Chong, Tao Wang, Hsiao-Mei Lu, Sara Seidler, Hong Lu, Steven Keiles, Elizabeth C. Chao, A. J. Stuenkel, Xiang Li, Aaron M. Elliott

published 15 May 2014

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Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

Yun Ji, Natalie Abrams, Wei Zhu, Eddie Salinas, Zhiya Yu, Douglas C. Palmer, Parthav Jailwala, Zulmarie Franco, Rahul Roychoudhuri, Eric Stahlberg, Luca Gattinoni, Nicholas P. Restifo

published 14 May 2014

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Analysis of Transposable Elements in the Genome of Asparagus officinalis from High Coverage Sequence Data

Shu-Fen Li, Wu-Jun Gao, Xin-Peng Zhao, Tian-Yu Dong, Chuan-Liang Deng, Long-Dou Lu

published 08 May 2014

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A Method Enabling High-Throughput Sequencing of Human Cytomegalovirus Complete Genomes from Clinical Isolates

Steven Sijmons, Kim Thys, Michaël Corthout, Ellen Van Damme, Marnix Van Loock, Stefanie Bollen, Sylvie Baguet, Jeroen Aerssens, Marc Van Ranst, Piet Maes

published 22 Apr 2014

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FANSe2: A Robust and Cost-Efficient Alignment Tool for Quantitative Next-Generation Sequencing Applications

Chuan-Le Xiao, Zhi-Biao Mai, Xin-Lei Lian, Jia-Yong Zhong, Jing-jie Jin, Qing-Yu He, Gong Zhang

published 17 Apr 2014

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