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Neuroprotectives

Emphasizing the role of oxidative stress and Sirt-1/Nrf2 and TLR-4/NF-κB in Tamarix aphylla mediated neuroprotective potential in rotenone-induced Parkinson’s disease: In silico and in vivo study

Dalia H. Abu-Baih, Abeer H. Elmaidomy, Hesham A. Abou-Zied, Nahla Abdelghany Hussien, Manar I. Rasekh, Entesar A. Saber, Sayed Fouad El-sheikh Ali, Mostafa E. Rateb, Omnia Magdy Hendawy, Faisal H. Altemani, Abdullah H. Altemani, Gerhard Bringmann, Usama Ramadan Abdelmohsen, Omnia Hesham Abdelhafez

published 06 Jan 2026

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The absence or the pharmacological blockade of the aryl hydrocarbon receptor promotes neuroprotection in the hippocampus after an ischemic insult

Rolando Castañeda-Arellano, Lucia García-Lara, Quetzalli D. Angeles-López, Francisca Pérez-Severiano, Guillermo Elizondo-Azuela, Sergio H. Dueñas-Jimenez, Sirenia González-Pozos, Irene G. Aguilar-García, Jose Segovia

published 26 Dec 2025

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Pharmacologic neuroprotective agents for the treatment of perinatal asphyxia in low-income and lower-middle-income countries: A systematic review and meta-analysis of randomised controlled trials

Victor Ayodeji Ayeni, Aisha Adam Abdullahi, Abdulmuminu Isah, Love Bukola Ayamolowo, Timothy Adeyemi, Motunrayo Adebukunola Oladimeji, Ufuoma Shalom Ahwinahwi, Vitalis Ikenna Chukwuike, Oluchukwu Perpetual Okeke, Olunike Rebecca Abodunrin, Folahanmi Tomiwa Akinsolu, Olajide Odunayo Sobande

published 04 Dec 2025

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Studies in rats of a target specific and reversible general anesthetic with a favorable safety profile

Zheng Xie, Robert Fong, Aaron P. Fox

published 04 Nov 2025

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Mechanistic insights into the anti-aging effects of Crocus sativus in a D-Gal-induced in vitro neural senescence model

Vanessa Castelli, Patrizia Cesare, Erjola Bej, Michele d’Angelo, Anna Rita Volpe

published 16 Jul 2025

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Effect of intranasal administration of Erigeron annuus and Carthamus tinctorius extracts in a rat model of olfactory dysfunction induced by 3-methylindole

Myeongguk Jeong, Hyeokjin Kwon, Yeeun Kim, Kyung-Yae Hyun, Yeongdon Ju, Go-Eun Choi, Chulhun L. Chang

published 10 Jun 2025

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Vigna radiata extracts in pumpkin and soya bean oil: A novel therapeutic approach for Alzheimer’s disease

Haroon Amin, Shazia Anwer Bukhari, Zunera Chauhdary, Naheed Akhter, Maria Saleem

published 15 Apr 2025

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Steroid, thiamine, and ascorbic acid during post-resuscitation period for comatose out-of-hospital cardiac arrest survivors (STAR) trial: Protocol for a clinical trial

Youn-Jung Kim, Byuk Sung Ko, Young-Il Roh, Yong Hwan Kim, Won Young Kim

published 11 Apr 2025

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Parthenolide regulates microglial and astrocyte function in primary cultures from ALS mice and has neuroprotective effects on primary motor neurons

Nadine Thau-Habermann, Thomas Gschwendtberger, Colin Bodemer, Susanne Petri

published 18 Mar 2025

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Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice

Giada Lavigna, Anna Grasso, Chiara Pasini, Valentina Grande, Laura Mignogna, Elena Restelli, Antonio Masone, Claudia Fracasso, Jacopo Lucchetti, Marco Gobbi, Roberto Chiesa

published 13 Jan 2025

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LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro

Robin Jansen, Marc Pawlitzki, Michael Gliem, Sven G. Meuth, Stefanie Schreiber, Michael-W. Görtler, Jens Neumann

published 09 Jan 2025

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Paracentrotus lividus sea urchin gonadal extract mitigates neurotoxicity and inflammatory signaling in a rat model of Parkinson’s disease

Nehal Shawky Nagy, Mohamed Helal, Eman Sheta Alsawy, Mohamad Moustafa Ali, Soheir Salem Al-Sherif, Amina Essawy Essawy

published 18 Dec 2024

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Anti-neuroinflammatory and neuroprotective potential of Cissus tuberosa ethanol extract in Parkinson’s disease model through the modulation of neuroinflammatory markers

Malik Saadullah, Amna Sehar, Zunera Chauhdary, Rida Siddique, Hafsa Tariq, Muhammad Asif, Shazia Anwer Bukhari, Aisha Sethi

published 06 Dec 2024

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