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Neuronal death

High frequency head impact exposure changes hippocampal sharp-wave ripple architecture

Daniel P. Chapman, Margaret S. Sten, Stefano Vicini, Mark P. Burns

published 09 Jan 2026

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Integrative Role of RNA N7-methylguanosine in epilepsy: Regulation of neuronal oxidative phosphorylation, programmed death and immune microenvironment

Jiangli Zhao, Qingyuan Sun, Xuchen Liu, Jiwei Wang, Ning Yang, Chao Li, Xinyu Wang

published 14 Jul 2025

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Daily high doses of atorvastatin alter neuronal morphology in a juvenile songbird model

Shuk C. Tsoi, Alicia C. Barrientos, David S. Vicario, Mimi L. Phan, Carolyn L. Pytte

published 28 Apr 2025

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Basic fibroblast growth factor helps protect facial nerve cells in a freeze-induced paralysis model

Shinji Iwata, Hiroyuki Yamada, Masato Teraoka, Takemichi Tanaka, Takuya Kimura, Tomonori Joko, Yasuhiko Tabata, Hiroyuki Wakisaka, Naohito Hato

published 06 Feb 2025

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LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro

Robin Jansen, Marc Pawlitzki, Michael Gliem, Sven G. Meuth, Stefanie Schreiber, Michael-W. Görtler, Jens Neumann

published 09 Jan 2025

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Stem cell factor restrains endoplasmic reticulum stress-associated apoptosis through c-Kit receptor activation of JAK2/STAT3 axis in hippocampal neuronal cells

Haiying Shen, Junjie Nie, Guangqing Li, Hongyan Tian, Jun Zhang, Xiaofeng Luo, Da Xu, Jie Sun, Dongfang Zhang, Hong Zhang, Guifang Zhao, Weiyao Wang, Zhonghua Zheng, Shuyan Yang, Yuji Jin

published 15 Nov 2024

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Prolactin protects hippocampal neurons against H₂O₂-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway

Fernando Macías, Miriam Ulloa, Carmen Clapp, Gonzalo Martínez de la Escalera, Edith Arnold

published 05 Nov 2024

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SARS-CoV-2 propagation to the TPH2-positive neurons in the ventral tegmental area induces cell death via GSK3β-dependent accumulation of phosphorylated tau

Motoki Imai, Fumitaka Kawakami, Takayuki Uematsu, Toshihide Matsumoto, Rei Kawashima, Yoshifumi Kurosaki, Shun Tamaki, Shotaro Maehana, Takafumi Ichikawa, Hideaki Hanaki, Hidero Kitazato, Makoto Kubo

published 30 Oct 2024

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Aβ_25-35-induced autophagy and apoptosis are prevented by the CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR signaling hub

Yingshi Ji, Jinghong Ren, Yuan Qian, Jiaxin Li, Huanyu Liu, Yuan Yao, Jianfeng Sun, Rajesh Khanna, Li Sun

published 26 Sep 2024

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Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson’s disease

Angela Minnella, Kevin P. McCusker, Akiko Amagata, Beatrice Trias, Marla Weetall, Joey C. Latham, Sloane O’Neill, Richard K. Wyse, Matthew B. Klein, Jeffrey K. Trimmer

published 18 Sep 2024

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Hspb1 and Lgals3 in spinal neurons are closely associated with autophagy following excitotoxicity based on machine learning algorithms

Lei Yan, Zihao Li, Chuanbo Li, Jingyu Chen, Xun Zhou, Jiaming Cui, Peng Liu, Chong Shen, Chu Chen, Hongxiang Hong, Guanhua Xu, Zhiming Cui

published 10 May 2024

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Identification of compounds that cause axonal dieback without cytotoxicity in dorsal root ganglia explants and intervertebral disc cells with potential to treat pain via denervation

Fei San Lee, Uyen N. Nguyen, Eliza J. Munns, Rebecca A. Wachs

published 02 May 2024

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Extracellular mixed histones are neurotoxic and modulate select neuroimmune responses of glial cells

Dylan E. Da Silva, Christy M. Richards, Seamus A. McRae, Ishvin Riar, Sijie (Shirley) Yang, Noah E. Zurfluh, Julien Gibon, Andis Klegeris

published 17 Apr 2024

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