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Myofilaments

Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure

Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Yasumasa Mototani, Megumi Nariyama, Aiko Ito, Ichiro Matsuo, Yoshio Hayakawa, Akinaka Morii, Takao Mitsubayashi, Yasutake Saeki, Yoshihiro Ishikawa, Satoshi Okumura

published 17 Jun 2025

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Assessment of dynamic cardiac repolarization and contractility in patients with hypertrophic cardiomyopathy

Andrew E. Radbill, Lucy Y. Lei, Sachin Y. Paranjape, Daniel J. Blackwell, Robert L. Abraham, Derek S. Chew, Satish R. Raj, Björn C. Knollmann

published 11 Feb 2021

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Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy

Louise L. A. M. Nijenkamp, Ilse A. E. Bollen, Hans W. M. Niessen, Cris G. dos Remedios, Michelle Michels, Corrado Poggesi, Carolyn Y. Ho, Diederik W. D. Kuster, Jolanda van der Velden

published 05 May 2020

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Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment

Amelia S. Power, Ruth Norman, Timothy L. M. Jones, Anthony J. Hickey, Marie-Louise Ward

published 09 Apr 2019

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nNOS splice variants differentially regulate myofilament function but are dispensable for intracellular calcium and force transients in cardiac papillary muscles

W. Glenn L. Kerrick, Yuanyuan Xu, Justin M. Percival

published 20 Jul 2018

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Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility

Kimberly Spaulding, Kiyoaki Takaba, Alexander Collins, Farshid Faraji, Guanying Wang, Esteban Aguayo, Liang Ge, David Saloner, Arthur W. Wallace, Anthony J. Baker, David H. Lovett, Mark B. Ratcliffe

published 12 Feb 2018

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Effects of cross-bridge compliance on the force-velocity relationship and muscle power output

Axel J. Fenwick, Alexander M. Wood, Bertrand C. W. Tanner

published 28 Dec 2017

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Electro-mechanical dynamics of spiral waves in a discrete 2D model of human atrial tissue

Paul Brocklehurst, Haibo Ni, Henggui Zhang, Jianqiao Ye

published 16 May 2017

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A mathematical model for active contraction in healthy and failing myocytes and left ventricles

Li Cai, Yongheng Wang, Hao Gao, Yiqiang Li, Xiaoyu Luo

published 13 Apr 2017

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The Inotropic Effect of the Active Metabolite of Levosimendan, OR-1896, Is Mediated through Inhibition of PDE3 in Rat Ventricular Myocardium

Øivind Ørstavik, Ornella Manfra, Kjetil Wessel Andressen, Geir Øystein Andersen, Tor Skomedal, Jan-Bjørn Osnes, Finn Olav Levy, Kurt Allen Krobert

published 04 Mar 2015

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Evidence of Specialized Tissue in Human Interatrial Septum: Histological, Immunohistochemical and Ultrastructural Findings

Lubov B. Mitrofanova, Andrey N. Gorshkov, Dmitry S. Lebedev, Evgeny N. Mikhaylov

published 20 Nov 2014

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RhoA/ROCK Signaling and Pleiotropic α_1A-Adrenergic Receptor Regulation of Cardiac Contractility

Ze-Yan Yu, Ju-Chiat Tan, Aisling C. McMahon, Siiri E. Iismaa, Xiao-Hui Xiao, Scott H. Kesteven, Melissa E. Reichelt, Marion C. Mohl, Nicola J. Smith, Diane Fatkin, David Allen, Stewart I. Head, Robert M. Graham, Michael P. Feneley

published 11 Jun 2014

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Apelin Increases Cardiac Contractility via Protein Kinase Cε- and Extracellular Signal-Regulated Kinase-Dependent Mechanisms

Ábel Perjés, Réka Skoumal, Olli Tenhunen, Attila Kónyi, Mihály Simon, Iván G. Horváth, Risto Kerkelä, Heikki Ruskoaho, István Szokodi

published 02 Apr 2014

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