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Myeloma cells

Serum proteomic profiling reveals MTA2 and AGO2 as potential prognostic biomarkers associated with disease activity and adverse outcomes in multiple myeloma

Dollapak Apipongrat, Sittiruk Roytrakul, Kannadit Prayongratana, Mongkon Charoenpitakchai, Kamphon Intharanut, Chonlada Laoruangroj, Panachai Silpsamrit, Oytip Nathalang

published 01 Dec 2022

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Relevance of diffusion-weighted imaging with background body signal suppression for staging, prognosis, morphology, treatment response, and apparent diffusion coefficient in plasma-cell neoplasms: A single-center, retrospective study

Akiko Yamada, Yoichi Araki, Yuko Tanaka, Shunsuke Otsuki, Arisa Yamada, Mitsuru Moriyama, Seiichiro Katagiri, Tamiko Suguro, Michiyo Asano, Seiichiro Yoshizawa, Daigo Akahane, Nahoko Furuya, Hiroaki Fujimoto, Seiichi Okabe, Moritaka Gotoh, Kunihito Suzuki, Kazuhiro Saito, Akihiko Gotoh

published 09 Jul 2021

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CRISPR/Cas9 mediated knock-out of VPREB1 gene induces a cytotoxic effect in myeloma cells

Mai Khaled, Amr S. Moustafa, Nashwa El-Khazragy, Maha Imam Ahmed, Marwa Ali Abd Elkhalek, Eman M. El_Salahy

published 08 Jan 2021

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APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression

Hiroyuki Yamazaki, Kotaro Shirakawa, Tadahiko Matsumoto, Yasuhiro Kazuma, Hiroyuki Matsui, Yoshihito Horisawa, Emani Stanford, Anamaria Daniela Sarca, Ryutaro Shirakawa, Keisuke Shindo, Akifumi Takaori-Kondo

published 08 Jan 2020

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ARQ-197, a small-molecule inhibitor of c-Met, reduces tumour burden and prevents myeloma-induced bone disease in vivo

Darren L. Lath, Clive H. Buckle, Holly R. Evans, Matthew Fisher, Jenny M. Down, Michelle A. Lawson, Andrew D. Chantry

published 20 Jun 2018

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TGF-β contamination of purified recombinant GDF15

Oddrun Elise Olsen, Anette Skjærvik, Berit Fladvad Størdal, Anders Sundan, Toril Holien

published 21 Nov 2017

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The KISS1 Receptor as an In Vivo Microenvironment Imaging Biomarker of Multiple Myeloma Bone Disease

Julia Dotterweich, Robert J. Tower, Andreas Brandl, Marc Müller, Lorenz C. Hofbauer, Andreas Beilhack, Regina Ebert, Claus C. Glüer, Sanjay Tiwari, Norbert Schütze, Franz Jakob

published 09 May 2016

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Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma

Adil Doganay Duru, Tolga Sutlu, Ann Wallblom, Katarina Uttervall, Johan Lund, Birgitta Stellan, Gösta Gahrton, Hareth Nahi, Evren Alici

published 17 Sep 2015

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Lipopolysaccharide-Induced CXCL10 mRNA Level and Six Stimulant-mRNA Combinations in Whole Blood: Novel Biomarkers for Bortezomib Responses Obtained from a Prospective Multicenter Trial for Patients with Multiple Myeloma

Takashi Watanabe, Masato Mitsuhashi, Morihiko Sagawa, Masaki Ri, Kenshi Suzuki, Masahiro Abe, Ken Ohmachi, Yasunori Nakagawa, Shingen Nakamura, Mizuki Chosa, Shinsuke Iida, Masahiro Kizaki

published 26 Jun 2015

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Different Associations of CD45 Isoforms with STAT3, PKC and ERK Regulate IL-6-Induced Proliferation in Myeloma

Xu Zheng, Allison S. Li, Huanyu Zheng, Dongmei Zhao, Dagang Guan, Huawei Zou

published 17 Mar 2015

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NOD/SCID-GAMMA Mice Are an Ideal Strain to Assess the Efficacy of Therapeutic Agents Used in the Treatment of Myeloma Bone Disease

Michelle A. Lawson, Julia M. Paton-Hough, Holly R. Evans, Rebecca E. Walker, William Harris, Dharshi Ratnabalan, John A. Snowden, Andrew D. Chantry

published 13 Mar 2015

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A Novel Phthalimide Derivative, TC11, Has Preclinical Effects on High-Risk Myeloma Cells and Osteoclasts

Maiko Matsushita, Yoshie Ozaki, Yuka Hasegawa, Fukiko Terada, Noriko Tabata, Hirokazu Shiheido, Hiroshi Yanagawa, Tsukasa Oikawa, Koichi Matsuo, Wenlin Du, Taketo Yamada, Masashi Hozumi, Daiju Ichikawa, Yutaka Hattori

published 24 Jan 2015

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Establishment of a Murine Graft-versus-Myeloma Model Using Allogeneic Stem Cell Transplantation

Marilène Binsfeld, Yves Beguin, Ludovic Belle, Eléonore Otjacques, Muriel Hannon, Alexandra Briquet, Roy Heusschen, Pierre Drion, Jenny Zilberberg, Bjarne Bogen, Frédéric Baron, Jo Caers

published 21 Nov 2014

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