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Mutation databases

Proteochemometric Modeling of the Susceptibility of Mutated Variants of the HIV-1 Virus to Reverse Transcriptase Inhibitors

Muhammad Junaid, Maris Lapins, Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg

published 15 Dec 2010

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DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A

Lotte Coelmont, Xavier Hanoulle, Udayan Chatterji, Carola Berger, Joke Snoeck, Michael Bobardt, Precious Lim, Inge Vliegen, Jan Paeshuyse, Grégoire Vuagniaux, Anne-Mieke Vandamme, Ralf Bartenschlager, Philippe Gallay, Guy Lippens, Johan Neyts

published 27 Oct 2010

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Molecular Diagnosis of Neonatal Diabetes Mellitus Using Next-Generation Sequencing of the Whole Exome

Amélie Bonnefond, Emmanuelle Durand, Olivier Sand, Franck De Graeve, Sophie Gallina, Kanetee Busiah, Stéphane Lobbens, Albane Simon, Christine Bellanné-Chantelot, Louis Létourneau, Raphael Scharfmann, Jérôme Delplanque, Robert Sladek, Michel Polak, Martine Vaxillaire, Philippe Froguel

published 26 Oct 2010

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Correlation Analysis for Protein Evolutionary Family Based on Amino Acid Position Mutations and Application in PDZ Domain

Qi-Shi Du, Cheng-Hua Wang, Si-Ming Liao, Ri-Bo Huang

published 06 Oct 2010

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Targeted Therapy Database (TTD): A Model to Match Patient's Molecular Profile with Current Knowledge on Cancer Biology

Simone Mocellin, Jeff Shrager, Richard Scolyer, Sandro Pasquali, Daunia Verdi, Francesco M. Marincola, Marta Briarava, Randy Gobbel, Carlo Rossi, Donato Nitti

published 10 Aug 2010

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A Critical Tryptophan and Ca²⁺ in Activation and Catalysis of TPPI, the Enzyme Deficient in Classic Late-Infantile Neuronal Ceroid Lipofuscinosis

Salomon Kuizon, Kathleen DiMaiuta, Marius Walus, Edmund C. Jenkins Jr, Marisol Kuizon, Elizabeth Kida, Adam A. Golabek, Daniel O. Espinoza, Raju K. Pullarkat, Mohammed A. Junaid

published 03 Aug 2010

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Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

Sungsam Gong, Tom L. Blundell

published 12 Feb 2010

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Bi-Directional SIFT Predicts a Subset of Activating Mutations

William Lee, Yan Zhang, Kiran Mukhyala, Robert A. Lazarus, Zemin Zhang

published 14 Dec 2009

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Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

Anshuman Dixit, Lin Yi, Ragul Gowthaman, Ali Torkamani, Nicholas J. Schork, Gennady M. Verkhivker

published 16 Oct 2009

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Oncogene Mutations, Copy Number Gains and Mutant Allele Specific Imbalance (MASI) Frequently Occur Together in Tumor Cells

Junichi Soh, Naoki Okumura, William W. Lockwood, Hiromasa Yamamoto, Hisayuki Shigematsu, Wei Zhang, Raj Chari, David S. Shames, Ximing Tang, Calum MacAulay, Marileila Varella-Garcia, Tõnu Vooder, Ignacio I. Wistuba, Stephen Lam, Rolf Brekken, Shinichi Toyooka, John D. Minna, Wan L. Lam, Adi F. Gazdar

published 14 Oct 2009

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Transitions at CpG Dinucleotides, Geographic Clustering of TP53 Mutations and Food Availability Patterns in Colorectal Cancer

Fabio Verginelli, Faraz Bishehsari, Francesco Napolitano, Mahboobeh Mahdavinia, Alessandro Cama, Reza Malekzadeh, Gennaro Miele, Giancarlo Raiconi, Roberto Tagliaferri, Renato Mariani-Costantini

published 31 Aug 2009

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Drug Resistance Mutations for Surveillance of Transmitted HIV-1 Drug-Resistance: 2009 Update

Diane E. Bennett, Ricardo J. Camacho, Dan Otelea, Daniel R. Kuritzkes, Hervé Fleury, Mark Kiuchi, Walid Heneine, Rami Kantor, Michael R. Jordan, Jonathan M. Schapiro, Anne-Mieke Vandamme, Paul Sandstrom, Charles A. B. Boucher, David van de Vijver, Soo-Yon Rhee, Tommy F. Liu, Deenan Pillay, Robert W. Shafer

published 06 Mar 2009

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Epidemiology of Doublet/Multiplet Mutations in Lung Cancers: Evidence that a Subset Arises by Chronocoordinate Events

Zhenbin Chen, Jinong Feng, Carolyn H. Buzin, Steve S. Sommer

published 13 Nov 2008

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