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Mutation databases

BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications

Dora Dias-Santagata, Quynh Lam, Kathy Vernovsky, Natalie Vena, Jochen K. Lennerz, Darrell R. Borger, Tracy T. Batchelor, Keith L. Ligon, A. John Iafrate, Azra H. Ligon, David N. Louis, Sandro Santagata

published 29 Mar 2011

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K70Q Adds High-Level Tenofovir Resistance to “Q151M Complex” HIV Reverse Transcriptase through the Enhanced Discrimination Mechanism

Atsuko Hachiya, Eiichi N. Kodama, Matthew M. Schuckmann, Karen A. Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G. Sarafianos

published 13 Jan 2011

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Detection of Resistance Mutations to Antivirals Oseltamivir and Zanamivir in Avian Influenza A Viruses Isolated from Wild Birds

Goran Orozovic, Kanita Orozovic, Johan Lennerstrand, Björn Olsen

published 06 Jan 2011

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Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis

Bernd Timmermann, Martin Kerick, Christina Roehr, Axel Fischer, Melanie Isau, Stefan T. Boerno, Andrea Wunderlich, Christian Barmeyer, Petra Seemann, Jana Koenig, Michael Lappe, Andreas W. Kuss, Masoud Garshasbi, Lars Bertram, Kathrin Trappe, Martin Werber, Bernhard G. Herrmann, Kurt Zatloukal, Hans Lehrach, Michal R. Schweiger

published 22 Dec 2010

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Proteochemometric Modeling of the Susceptibility of Mutated Variants of the HIV-1 Virus to Reverse Transcriptase Inhibitors

Muhammad Junaid, Maris Lapins, Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg

published 15 Dec 2010

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DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A

Lotte Coelmont, Xavier Hanoulle, Udayan Chatterji, Carola Berger, Joke Snoeck, Michael Bobardt, Precious Lim, Inge Vliegen, Jan Paeshuyse, Grégoire Vuagniaux, Anne-Mieke Vandamme, Ralf Bartenschlager, Philippe Gallay, Guy Lippens, Johan Neyts

published 27 Oct 2010

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Molecular Diagnosis of Neonatal Diabetes Mellitus Using Next-Generation Sequencing of the Whole Exome

Amélie Bonnefond, Emmanuelle Durand, Olivier Sand, Franck De Graeve, Sophie Gallina, Kanetee Busiah, Stéphane Lobbens, Albane Simon, Christine Bellanné-Chantelot, Louis Létourneau, Raphael Scharfmann, Jérôme Delplanque, Robert Sladek, Michel Polak, Martine Vaxillaire, Philippe Froguel

published 26 Oct 2010

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Correlation Analysis for Protein Evolutionary Family Based on Amino Acid Position Mutations and Application in PDZ Domain

Qi-Shi Du, Cheng-Hua Wang, Si-Ming Liao, Ri-Bo Huang

published 06 Oct 2010

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Targeted Therapy Database (TTD): A Model to Match Patient's Molecular Profile with Current Knowledge on Cancer Biology

Simone Mocellin, Jeff Shrager, Richard Scolyer, Sandro Pasquali, Daunia Verdi, Francesco M. Marincola, Marta Briarava, Randy Gobbel, Carlo Rossi, Donato Nitti

published 10 Aug 2010

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A Critical Tryptophan and Ca²⁺ in Activation and Catalysis of TPPI, the Enzyme Deficient in Classic Late-Infantile Neuronal Ceroid Lipofuscinosis

Salomon Kuizon, Kathleen DiMaiuta, Marius Walus, Edmund C. Jenkins Jr, Marisol Kuizon, Elizabeth Kida, Adam A. Golabek, Daniel O. Espinoza, Raju K. Pullarkat, Mohammed A. Junaid

published 03 Aug 2010

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Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

Sungsam Gong, Tom L. Blundell

published 12 Feb 2010

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Bi-Directional SIFT Predicts a Subset of Activating Mutations

William Lee, Yan Zhang, Kiran Mukhyala, Robert A. Lazarus, Zemin Zhang

published 14 Dec 2009

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Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

Anshuman Dixit, Lin Yi, Ragul Gowthaman, Ali Torkamani, Nicholas J. Schork, Gennady M. Verkhivker

published 16 Oct 2009

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