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Mutation databases

BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications

Dora Dias-Santagata, Quynh Lam, [ ... ], Sandro Santagata

K70Q Adds High-Level Tenofovir Resistance to “Q151M Complex” HIV Reverse Transcriptase through the Enhanced Discrimination Mechanism

Atsuko Hachiya, Eiichi N. Kodama, [ ... ], Stefan G. Sarafianos

Detection of Resistance Mutations to Antivirals Oseltamivir and Zanamivir in Avian Influenza A Viruses Isolated from Wild Birds

Goran Orozovic, Kanita Orozovic, Johan Lennerstrand, Björn Olsen

Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis

Bernd Timmermann, Martin Kerick, [ ... ], Michal R. Schweiger

Proteochemometric Modeling of the Susceptibility of Mutated Variants of the HIV-1 Virus to Reverse Transcriptase Inhibitors

Muhammad Junaid, Maris Lapins, [ ... ], Jarl E. S. Wikberg

DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A

Lotte Coelmont, Xavier Hanoulle, [ ... ], Johan Neyts

Molecular Diagnosis of Neonatal Diabetes Mellitus Using Next-Generation Sequencing of the Whole Exome

Amélie Bonnefond, Emmanuelle Durand, [ ... ], Philippe Froguel

Correlation Analysis for Protein Evolutionary Family Based on Amino Acid Position Mutations and Application in PDZ Domain

Qi-Shi Du, Cheng-Hua Wang, Si-Ming Liao, Ri-Bo Huang

Targeted Therapy Database (TTD): A Model to Match Patient's Molecular Profile with Current Knowledge on Cancer Biology

Simone Mocellin, Jeff Shrager, [ ... ], Donato Nitti

A Critical Tryptophan and Ca²⁺ in Activation and Catalysis of TPPI, the Enzyme Deficient in Classic Late-Infantile Neuronal Ceroid Lipofuscinosis

Salomon Kuizon, Kathleen DiMaiuta, [ ... ], Mohammed A. Junaid

Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

Sungsam Gong, Tom L. Blundell

Bi-Directional SIFT Predicts a Subset of Activating Mutations

William Lee, Yan Zhang, [ ... ], Zemin Zhang

Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

Anshuman Dixit, Lin Yi, [ ... ], Gennady M. Verkhivker

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