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Mouse models

Protective effect of cannabinoid type II receptor ligand on bleomycin-induced pulmonary fibrosis in mice

Cheng Cao, Run-Lin Wang, Chen-xin Guo, Xiao-wei Xu, Jia-hui Wei, Wen-zhuo Cheng, Yi-zhe Yu, Jia-jie Shi, Zhi-wei Feng, Yan Chen

published 27 Feb 2026

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Psmd13, a proteasome regulatory subunit identified in miR-29a regulation during neuronal differentiation

Diji Kuriakose, Grant Morahan, Zhi-cheng Xiao

published 24 Feb 2026

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A new mechanism regulating microglial NLRP3 inflammasome: FMR1 mediates NLRP3 mRNA stability

Qian Deng, Qianqian Bai, Yang Yang, Wenchao Tang, Fangfei Liu, Shumin Zhang, Hao Wang, Zhehua Xing, Chi Zhang, Yanhui Yang, Qizhi Fu, Hua Fan

published 20 Feb 2026

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Noradrenergic innervation across brain regions is altered by aging and by disease progression in a mouse model of Alzheimer’s disease neuropathology

Nicole M. Hernandez, Manuel Silva-Pérez, Jeannie Chin

published 18 Feb 2026

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An automated morphometric approach to evaluate distal lung patterning in mouse models of bronchopulmonary dysplasia

Declan J. Gainer, Mark L. Ormiston

published 17 Feb 2026

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CD47 blockade (ALX301) enhances immunoradiotherapy response in HPV negative head and neck squamous cell carcinoma

Abdula Monther, Riyam Al-Msari, Robert Saddawi-Konefka, Santiago Fassardi, Cynthia Tang, Chad Philips, Prakriti Sen, Pardis Mohammadzadeh, Kelsey Decker, Sayuri Miyauchi, Souvick Roy, Riley Jones, Xingyu Wu, Silvio Gutkind, Andrew Sharabi, Joseph Califano

published 17 Feb 2026

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Identifying optimal combination regimens for therapy of Mycobacterium tuberculosis with an algorithmic approach: prospective predictions and validations

Arnold Louie, Michael Neely, Sarah Kim, Charles A. Scanga, JoAnne L. Flynn, Charles A. Peloquin, Brendan Prideaux, Stephan Schmidt, Mohammed Almoslem, Walter Yamada, George Drusano

published 10 Feb 2026

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IL-22 inhibits ferroptosis and attenuates ischemia-reperfusion-induced acute kidney injury: Association with activation of the P62-Keap1-Nrf2 signaling pathway

Lin Zhang, Feng Luo, Yalin Chai, Lijie Sun, Xuan Wang, Le Yin, Congjuan Luo

published 06 Feb 2026

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Genetic ablation of interleukin-17A augments fibrosis in a mouse model of cholestatic liver injury

Takashi Kitagataya, Anuradha Krishnan, Kirsta E. Olson, Florencia Gutierrez, Michelle Baez-Faria, Maria Eugenia Guicciardi, Kevin D. Pavelko, Adiba I. Azad, Gregory J. Gores

published 06 Feb 2026

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RAF1 as a standalone therapeutic target in KRAS-driven lung adenocarcinoma: No added efficacy from co-targeting ARAF, EGFR, or DDR1

Laura de-la-Puente-Ovejero, Ana Fernández-Rodríguez, Sarah Francoz, Gonzalo Aizpurua, Lucía Lomba-Riego, Matthias Drosten, Carmen Guerra, Mónica Musteanu, Mariano Barbacid, Sara García-Alonso

published 06 Feb 2026

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Salt loading as a promising approach to study the dopaminergic phenotype of neurons of the supraoptic nucleus in mice

Alyona E. Bannikova, Tatiana S. Pronina, Dmitry V. Troshev, Vsevolod V. Bogdanov, Anna A. Kolacheva, Ekaterina N. Pavlova, Victor E. Blokhin, Varvara I. Kalashnikova, Michael V. Ugrumov

published 06 Feb 2026

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Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route

Sara C. Johnston, Anthony T. Ginnetti, Nancy A. Twenhafel, Sarah L. W. Norris, Shiying Chen, Josh L. Moore, Christopher W. Boyce, Ondraya M. Frick, Dave N. Dyer, Donald J. Marsh, Stephen C. Stevens, Walter F. Knapp, Kerry L. Berrier, Hui Wan, Gregory C. Adam, Timothy J. Hartingh, Heather L. Esham, Jimmy O. Fiallos, Eugene L. Blue, Willie B. Sifford, Jonathan D. Latty, Harold L. Mills, Nazira A. Alli, Ashley E. Piper, Aimee I. Goodson, J. Matthew Meinig, David B. Olsen, Linda A. Lieberman, Rekha G. Panchal

published 06 Feb 2026

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TGF-β1 relieves burn injury induced pain by alleviating inflammation in mouse

Shengfeng Gao, Mengting Wang, Lu Wang, Yasu Jiang, Peng Chen, Li Guo, Lili Ni, Fan Fei, Zhenhua Gong

published 05 Feb 2026

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