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Mouse models

Soluble ST2 Associates with Diabetes but Not Established Cardiovascular Risk Factors: A New Inflammatory Pathway of Relevance to Diabetes?

Ashley M. Miller, David Purves, Alex McConnachie, Darren L. Asquith, G. David Batty, Harry Burns, Jonathan Cavanagh, Ian Ford, Jennifer S. McLean, Chris J. Packard, Paul G. Shiels, Helen Turner, Yoga N. Velupillai, Kevin A. Deans, Paul Welsh, Iain B. McInnes, Naveed Sattar

published 24 Oct 2012

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Carnitine Deficiency in OCTN2^−/− Newborn Mice Leads to a Severe Gut and Immune Phenotype with Widespread Atrophy, Apoptosis and a Pro-Inflammatory Response

Srinivas Sonne, Prem S. Shekhawat, Dietrich Matern, Vadivel Ganapathy, Leszek Ignatowicz

published 24 Oct 2012

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Influenza Infects Lung Microvascular Endothelium Leading to Microvascular Leak: Role of Apoptosis and Claudin-5

Susan M. Armstrong, Changsen Wang, Jayesh Tigdi, Xiaoe Si, Carlo Dumpit, Steffany Charles, Asela Gamage, Theo J. Moraes, Warren L. Lee

published 24 Oct 2012

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Deletion of the gabra2 Gene Results in Hypersensitivity to the Acute Effects of Ethanol but Does Not Alter Ethanol Self Administration

Claire I. Dixon, Sophie E. Walker, Sarah L. King, David N. Stephens

published 24 Oct 2012

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Residual Tumor Cells That Drive Disease Relapse after Chemotherapy Do Not Have Enhanced Tumor Initiating Capacity

Ganapati V. Hegde, Cecile de la Cruz, Jeffrey Eastham-Anderson, Yanyan Zheng, E. Alejandro Sweet-Cordero, Erica L. Jackson

published 24 Oct 2012

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In Vivo Functional Requirement of the Mouse Ifitm1 Gene for Germ Cell Development, Interferon Mediated Immune Response and Somitogenesis

Ingeborg Klymiuk, Lukas Kenner, Thure Adler, Dirk H. Busch, Auke Boersma, Martin Irmler, Valérie Gailus-Durner, Helmut Fuchs, Nicole Leitner, Mathias Müller, Ralf Kühn, Michaela Schlederer, Irina Treise, Martin Hrabě de Angelis, Johannes Beckers

published 24 Oct 2012

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Taurine Provides Neuroprotection against Retinal Ganglion Cell Degeneration

Nicolas Froger, Lucia Cadetti, Henri Lorach, Joao Martins, Alexis-Pierre Bemelmans, Elisabeth Dubus, Julie Degardin, Dorothée Pain, Valérie Forster, Laurent Chicaud, Ivana Ivkovic, Manuel Simonutti, Stéphane Fouquet, Firas Jammoul, Thierry Léveillard, Ryad Benosman, José-Alain Sahel, Serge Picaud

published 24 Oct 2012

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Progression of Oral Squamous Cell Carcinoma Accompanied with Reduced E-Cadherin Expression but Not Cadherin Switch

Takashi Hashimoto, Yuichi Soeno, Genta Maeda, Yuji Taya, Takaaki Aoba, Masanori Nasu, Shuichi Kawashiri, Kazushi Imai

published 23 Oct 2012

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Isoflavones, Genistein and Daidzein, Regulate Mucosal Immune Response by Suppressing Dendritic Cell Function

John Wei, Shiven Bhatt, Lisa M. Chang, Hugh A. Sampson, Madhan Masilamani

published 22 Oct 2012

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Genomic Expression Analyses Reveal Lysosomal, Innate Immunity Proteins, as Disease Correlates in Murine Models of a Lysosomal Storage Disorder

Md. Suhail Alam, Michelle Getz, Innocent Safeukui, Sue Yi, Pamela Tamez, Jenny Shin, Peter Velázquez, Kasturi Haldar

published 19 Oct 2012

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Hyperglycaemia Exacerbates Choroidal Neovascularisation in Mice via the Oxidative Stress-Induced Activation of STAT3 Signalling in RPE Cells

Xia Li, Yan Cai, Yu-Sheng Wang, Yuan-Yuan Shi, Wei Hou, Chun-Sheng Xu, Hai-Yan Wang, Zi Ye, Li-Bo Yao, Jian Zhang

published 19 Oct 2012

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Inhibition of Hepatitis B Virus and Induction of Hepatoma Cell Apoptosis by ASGPR-Directed Delivery of shRNAs

Jingwei Ma, Chunmei Huang, Xinxin Yao, Chuan Shi, Lifang Sun, Lu Yuan, Ping Lei, Huifen Zhu, Hongbo Liu, Xiongwen Wu, Qin Ning, Chun Zhou, Guanxin Shen

published 19 Oct 2012

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Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells

Vivian L. de Oliveira, Romy R. M. C. Keijsers, Peter C. M. van de Kerkhof, Marieke M. B. Seyger, Esther Fasse, Lars Svensson, Markus Latta, Hanne Norsgaard, Tord Labuda, Pieter Hupkens, Piet E. J. van Erp, Irma Joosten, Hans J. P. M. Koenen

published 19 Oct 2012

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