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Mouse models

Evaluation of the anti-cancer efficacy of lipid nanoparticles containing siRNA against HPV16 E6/E7 combined with cisplatin in a xenograft model of cervical cancer

Sung Wan Kang, Ok-Ju Kang, Ji-young Lee, Hyejeong Kim, Hunsoon Jung, Hongjoong Kim, Shin-Wha Lee, Yong Man Kim, Eun Kyung Choi

published 16 Feb 2024

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Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming

Josh Jones, Qiaojuan Shi, Rahul R. Nath, Ilana L. Brito

published 16 Feb 2024

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PERK modulation, with GSK2606414, Sephin1 or salubrinal, failed to produce therapeutic benefits in the SOD1G93A mouse model of ALS

Fernando G. Vieira, Valerie R. Tassinari, Joshua D. Kidd, Andrew Moreno, Kenneth Thompson, Steven Perrin, Alan Gill, Theo Hatzipetros

published 15 Feb 2024

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Combined administration of anisodamine and neostigmine alleviated colitis by inducing autophagy and inhibiting inflammation

Mengzhen Liu, Danni Zhu, Hui Yan, Zhiwei Dong, Jingjing Zhang, Ni Kong, Guangyu Zhang, Qin Xu, Ting Han, Ping Ke, Chong Liu

published 14 Feb 2024

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A comparison of Bartonella henselae infection in immunocompetent and immunocompromised mice

Rebekah L. Bullard, Mercedes Cheslock, Shiva Kumar Goud Gadila, Ricardo G. Maggi, Edward B. Breitschwerdt, Ahmad A. Saied, Monica E. Embers

published 12 Feb 2024

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Agomelatine prevented depression in the chronic restraint stress model through enhanced catalase activity and halted oxidative stress

Jiaxi Xu, Cheng Zhu, Piaopiao Jin, Wangdi Sun, Enyan Yu

published 09 Feb 2024

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Time-course analysis of liver and serum galectin-3 in acute liver injury after alpha-galactosylceramide injection

Mikiko Matsuo, Ayumu Kanbe, Kei Noguchi, Ayumi Niwa, Yuko Imaizumi, Takahito Kuroda, Koki Ichihashi, Takafumi Okubo, Kosuke Mori, Tomohiro Kanayama, Hiroyuki Tomita, Akira Hara

published 08 Feb 2024

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Sex- and region-specific cortical and hippocampal whole genome transcriptome profiles from control and APP/PS1 Alzheimer’s disease mice

Anna Papazoglou, Christina Henseler, Sandra Weickhardt, Jenni Teipelke, Panagiota Papazoglou, Johanna Daubner, Teresa Schiffer, Damian Krings, Karl Broich, Jürgen Hescheler, Agapios Sachinidis, Dan Ehninger, Catharina Scholl, Britta Haenisch, Marco Weiergräber

published 07 Feb 2024

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Perinatal choline supplementation prevents learning and memory deficits and reduces brain amyloid Aβ42 deposition in App^NL-G-F Alzheimer’s disease model mice

Thomas A. Bellio, Jessenia Y. Laguna-Torres, Mary S. Campion, Jay Chou, Sheila Yee, Jan K. Blusztajn, Tiffany J. Mellott

published 05 Feb 2024

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Aromatase deficiency in transplanted bone marrow cells improves vertebral trabecular bone quantity, connectivity, and mineralization and decreases cortical porosity in murine bone marrow transplant recipients

Katie Rubitschung, Amber Sherwood, Rasesh Kapadia, Yin Xi, Asghar Hajibeigi, Katya B. Rubinow, Joseph E. Zerwekh, Orhan K. Öz

published 05 Feb 2024

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Characterization and comparison of human and mouse milk cells

Rose Doerfler, Saigopalakrishna Yerneni, Alexandra Newby, Namit Chaudhary, Ashley Shu, Katherine Fein, Juliana Hofstatter Azambuja, Kathryn A. Whitehead

published 31 Jan 2024

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Chloroquine decreases cardiac fibrosis and improves cardiac function in a mouse model of Duchenne muscular dystrophy

Takuya Hirata, Shiro Baba, Kentaro Akagi, Koichi Matsuda, Katsutsugu Umeda, Souichi Adachi, Toshio Heike, Junko Takita

published 31 Jan 2024

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A murine model to evaluate immunotherapy effectiveness for human Fanconi anemia-mutated acute myeloid leukemia

Tingting Huang, Bernice Leung, Yuyang Huang, Laura Price, Jiang Gui, Bonnie W. Lau

published 30 Jan 2024

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