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Motor neurons

Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline

Shweta Tendulkar, Tong Wu, Amy Strickland, Amber R. Hackett, Yurie Sato-Yamada, Xianrong Mao, Yo Sasaki, Jeffrey Milbrandt, A. Joseph Bloom, Aaron DiAntonio

published 17 Apr 2026

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Impaired dynein function preserves spinal interneuron survival and positioning in an ALS-like mouse model

Eleni Christoforidou, Jordan S. Rowe, Fabio A. Simoes, Raphaelle Cassel, Luc Dupuis, Peter Nigel Leigh, Majid Hafezparast

published 02 Apr 2026

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Exposure to the organochlorine pesticide cis-chlordane induces ALS-like mitochondrial perturbations in stem cell-derived motor neurons

Oliver Clackson, Muhammad Reza Hamid, Adithi Wijesekera, Daniel Kulick, Alison Linsley O’Neil

published 14 Oct 2025

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The molecular components of the anti-inflammatory cholinergic pathway are extrasplenic

Warda Merchant, Steven Wyler, Bandy Chen, Laurent Gautron

published 05 Sep 2025

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Loss of Ufsp1 does not cause major changes at the neuromuscular junction

Cristofer Calvo, Coalesco Smith, Taejeong Song, Fabian Montecino-Morales, Sakthivel Sadayappan, Douglas P. Millay, Minchul Kim

published 01 Aug 2025

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Tailoring neuromuscular dynamics: A modeling framework for realistic sEMG simulation

Alvaro Costa-Garcia, Shingo Shimoda, Akihiko Murai

published 12 Jun 2025

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Autophagy across tissues of aging mice

Julian M. Carosi, Alexis Martin, Leanne K. Hein, Sofia Hassiotis, Kathryn J. Hattersley, Bradley J. Turner, Célia Fourrier, Julien Bensalem, Timothy J. Sargeant

published 04 Jun 2025

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Findings from transcriptomics and immunohistochemistry indicate an autoimmune disease targeting brainstem inhibitory interneurons in bovine spastic paresis

Frederik Krull, Shahrbanou Hosseini, Martina Bleyer, Bertram Brenig

published 29 May 2025

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Developmental and neurobehavioral toxicity of benzotriazole ultraviolet stabilizer UV-360 on zebrafish larvae

Lihan Xu, Donglai Sheng, Rong He, Yanlong Meng, Lili Tian, Yuhao Luo, Yingjia Wang, Rusidanmu Aizemaiti, Zhou An, Yuying Wang

published 23 May 2025

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Parthenolide regulates microglial and astrocyte function in primary cultures from ALS mice and has neuroprotective effects on primary motor neurons

Nadine Thau-Habermann, Thomas Gschwendtberger, Colin Bodemer, Susanne Petri

published 18 Mar 2025

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Single-unit activity in the anterior claustrum during memory retrieval after trace fear conditioning

Sewon Park, Kuenbae Sohn, Donghyeon Yoon, Junghwa Lee, Sukwoo Choi

published 11 Feb 2025

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Optimal sigmoid function models for analysis of transspinal evoked potential recruitment curves recorded from different muscles

Andreas Skiadopoulos, Maria Knikou

published 22 Jan 2025

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In vivo mapping of sodium homeostasis disturbances in individual ALS patients: A brain ²³Na MRI study

Aude-Marie Grapperon, Mohamed Mounir El Mendili, Adil Maarouf, Jean-Philippe Ranjeva, Maxime Guye, Annie Verschueren, Shahram Attarian, Wafaa Zaaraoui

published 22 Jan 2025

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