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Molecular probe techniques

TAS2R5 screening reveals biased agonism that fails to evoke internalization and downregulation resulting in attenuated desensitization

Donghwa Kim, Hannah R. Strzelinski, Stephen B. Liggett

published 13 Feb 2025

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Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions

Zac Sandy, Zijuan Wang, Deepak Behera, Benjamin M. Foster, Finlay A. Martin, Kira Brüninghoff, Kathleen M. Cain, Wolfgang Dörner, Maria Jose Cabello-Lobato, Josep V. Forment, Matthew J. Cliff, Igor Larrosa, Perdita Barran, Duncan L. Smith, Henning D. Mootz, Christine K. Schmidt

published 27 Jan 2025

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Microbiota-derived proteins synergize with IL-23 to drive IL22 production in model type 3 innate lymphoid cells

Yanling Wang, David S. J. Allan, Andrew T. Gewirtz

published 13 Jan 2025

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Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation

Michael O. Isei, Meredith Crockett, Emily Chen, Joel Rodwell-Bullock, Trae Carroll, Peter A. Girardi, Keith Nehrke, Gail V. W. Johnson

published 03 Jan 2025

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The performance of a lateral flow SARS-CoV-2 antibody assay and semi-autonomous SARS-CoV-2 antisense and sense RNA fluorescence in situ hybridization assay in a prospective cohort pilot study within a Dutch military population

Inge D. Wijnberg, Anton J. Soons, Johan G. Reimerink, Marit Wiersma, Marie Christine J. Plat, Tom van Gool, Gijsbert J. Jansen, Cornelis Stijnis, Jack G. Koning, Adam Meijer

published 31 Dec 2024

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Dissociation of mitochondrial and ribosomal biogenesis during thallium administration in rat kidney

Sho Sugahara, Kana Unuma, Shuheng Wen, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura

published 04 Dec 2024

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The NF-κB-HE4 axis: A novel regulator of HE4 secretion in ovarian cancer

Kyukwang Kim, Negar Khazan, Jamie L. McDowell, Cameron W. A. Snyder, John P. Miller, Rakesh K. Singh, Michelle E. Whittum, Rachael Turner, Richard G. Moore

published 02 Dec 2024

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The endometrial cancer A230V-ALK5 (TGFBR1) mutant attenuates TGF-β signaling and exhibits reduced in vitro sensitivity to ALK5 inhibitors

Eun-Jeong Yu, Daphne W. Bell

published 22 Nov 2024

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Investigation of Astyanax mexicanus (Characiformes, Characidae) chromosome 1 structure reveals unmapped sequences and suggests conserved evolution

Maelin Silva, Duílio Mazzoni Zerbinato Andrade Silva, Jonathan Pena Castro, Alex I. Makunin, Felipe Faix Barby, Edivaldo Herculano Correa de Oliveira, Thomas Liehr, Marcelo Bello Cioffi, Fábio Porto-Foresti, Fausto Foresti, Roberto Ferreira Artoni

published 18 Nov 2024

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Comparative analysis of whole exome sequencing kits for the canine genome

Jinhee Jang, Yong-Jik Lee, Soohyun Ko, A. M. Abd El-Aty, Ibrahim Gecili, Ji Hoon Jeong, ChangHyuk Kwon, Tae Woo Jung

published 04 Nov 2024

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A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery

Philip R. Coryell, Paul B. Hardy, Susan Chubinskaya, Kenneth H. Pearce, Richard F. Loeser

published 01 Nov 2024

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Monocarboxylate transporter dependent mechanism is involved in proliferation, migration, and invasion of human glioblastoma cell lines via activation of PI3K/Akt signaling pathway

Chen Gao, Binni Yang, Yurong Li, Wenjuan Pei

published 30 Oct 2024

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Unveiling scientific articles from paper mills with provenance analysis

João Phillipe Cardenuto, Daniel Moreira, Anderson Rocha

published 30 Oct 2024

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