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Microsomes

A Cell-Free Translocation System Using Extracts of Cultured Insect Cells to Yield Functional Membrane Proteins

Toru Ezure, Kei Nanatani, Yoko Sato, Satomi Suzuki, Keishi Aizawa, Satoshi Souma, Masaaki Ito, Takahiro Hohsaka, Gunnar von Heijine, Toshihiko Utsumi, Keietsu Abe, Eiji Ando, Nobuyuki Uozumi

published 08 Dec 2014

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Dual Effects of Ketoconazole cis-Enantiomers on CYP3A4 in Human Hepatocytes and HepG2 Cells

Aneta Novotná, Kristýna Krasulová, Iveta Bartoňková, Martina Korhoňová, Petr Bachleda, Pavel Anzenbacher, Zdeněk Dvořák

published 24 Oct 2014

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Characterization of the Commercially-Available Fluorescent Chloroquine-BODIPY Conjugate, LynxTag-CQ_GREEN, as a Marker for Chloroquine Resistance and Uptake in a 96-Well Plate Assay

Cheryl C. Y. Loh, Rossarin Suwanarusk, Yan Quan Lee, Kitti W. K. Chan, Kit-Ying Choy, Laurent Rénia, Bruce Russell, Martin J. Lear, François H. Nosten, Kevin S. W. Tan, Larry M. C. Chow

published 24 Oct 2014

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Modulation of Cytochrome P450 Metabolism and Transport across Intestinal Epithelial Barrier by Ginger Biophenolics

Rao Mukkavilli, Sushma R. Gundala, Chunhua Yang, Shashikiran Donthamsetty, Guilherme Cantuaria, Gajanan R. Jadhav, Subrahmanyam Vangala, Michelle D. Reid, Ritu Aneja

published 24 Sep 2014

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Structure-Function Analysis of Porcine Cytochrome P450 3A29 in the Hydroxylation of T-2 Toxin as Revealed by Docking and Mutagenesis Studies

Guyue Cheng, Changcun Liu, Xu Wang, Hongmin Ma, Yuanhu Pan, Lingli Huang, Haihong Hao, Menghong Dai, Zonghui Yuan

published 03 Sep 2014

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Modulation of CYP1A1 and CYP1A2 Hepatic Enzymes after Oral Administration of Chios Mastic Gum to Male Wistar Rats

Efrosini S. Katsanou, Katerina Kyriakopoulou, Christina Emmanouil, Nikolas Fokialakis, Alexios-Leandros Skaltsounis, Kyriaki Machera

published 20 Jun 2014

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Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention Relationships

Mariusz Belka, Weronika Hewelt-Belka, Jarosław Sławiński, Tomasz Bączek

published 03 Jun 2014

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Sorafenib Metabolism Is Significantly Altered in the Liver Tumor Tissue of Hepatocellular Carcinoma Patient

Ling Ye, Xiaoshan Yang, Enshuang Guo, Weiying Chen, Linlin Lu, Ying Wang, Xiaojuan Peng, Tongmeng Yan, Fuyan Zhou, Zhongqiu Liu

published 05 May 2014

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In Vitro Metabolism of 20(R)-25-Methoxyl-Dammarane-3, 12, 20-Triol from Panax notoginseng in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes

Xiangrong Zhang, Ji Zhang, Wei Li, Li Liu, Baoshan Sun, Zhenghong Guo, Caihong Shi, Yuqing Zhao

published 15 Apr 2014

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A New Assay for Determining Ganglioside Sialyltransferase Activities Lactosylceramide-2,3-Sialyltransferase (SAT I) and Monosialylganglioside-2,3-Sialyltransferase (SAT IV)

Cynthia Q. Sun, Ulrike Hubl, Petra Hoefakker, Madhusudan K. Vasudevamurthy, Keryn D. Johnson

published 09 Apr 2014

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In Vitro Evaluation of the Inhibitory Potential of Pharmaceutical Excipients on Human Carboxylesterase 1A and 2

Chengliang Zhang, Yanjiao Xu, Qiaoni Zhong, Xiping Li, Ping Gao, Chengyang Feng, Qian Chu, Yuan Chen, Dong Liu

published 03 Apr 2014

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The Curious Case of Benzbromarone: Insight into Super-Inhibition of Cytochrome P450

Abhinav Parashar, Sudeep Kumar Gade, Mahesh Potnuru, Nandita Madhavan, Kelath Murali Manoj

published 03 Mar 2014

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Inhibition of Baicalin on Metabolism of Phenacetin, a Probe of CYP1A2, in Human Liver Microsomes and in Rats

Na Gao, Bing Qi, Fang-jun Liu, Yan Fang, Jun Zhou, Lin-jing Jia, Hai-ling Qiao

published 26 Feb 2014

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