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Microsomes

Functional Characterization of the Vitamin K₂ Biosynthetic Enzyme UBIAD1

Yoshihisa Hirota, Kimie Nakagawa, [ ... ], Toshio Okano

A Fungal P450 (CYP5136A3) Capable of Oxidizing Polycyclic Aromatic Hydrocarbons and Endocrine Disrupting Alkylphenols: Role of Trp¹²⁹ and Leu³²⁴

Khajamohiddin Syed, Aleksey Porollo, Ying Wai Lam, Jagjit S. Yadav

In Vitro Evaluation of the Inhibitory Potential of Pharmaceutical Excipients on Human Carboxylesterase 1A and 2

Chengliang Zhang, Yanjiao Xu, [ ... ], Dong Liu

Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs

Hao Sun, David W. Piotrowski, [ ... ], Alfin D. N. Vaz

Dual Effects of Ketoconazole cis-Enantiomers on CYP3A4 in Human Hepatocytes and HepG2 Cells

Aneta Novotná, Kristýna Krasulová, [ ... ], Zdeněk Dvořák

Sorafenib Metabolism Is Significantly Altered in the Liver Tumor Tissue of Hepatocellular Carcinoma Patient

Ling Ye, Xiaoshan Yang, [ ... ], Zhongqiu Liu

Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders

Bitna Yi, Alam Jahangir, [ ... ], Mehrdad Shamloo

The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic Reticulum

Yifat Cohen, Márton Megyeri, [ ... ], Maya Schuldiner

A Knockout Mutation of a Constitutive GPCR in Tetrahymena Decreases Both G-Protein Activity and Chemoattraction

Thomas J. Lampert, Kevin D. Coleman, Todd M. Hennessey

Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention Relationships

Mariusz Belka, Weronika Hewelt-Belka, Jarosław Sławiński, Tomasz Bączek

Characterisation of a Desmosterol Reductase Involved in Phytosterol Dealkylation in the Silkworm, Bombyx mori

Leonora F. Ciufo, Patricia A. Murray, [ ... ], Huw H. Rees

Inhibition of Baicalin on Metabolism of Phenacetin, a Probe of CYP1A2, in Human Liver Microsomes and in Rats

Na Gao, Bing Qi, [ ... ], Hai-ling Qiao

Characterization of the Commercially-Available Fluorescent Chloroquine-BODIPY Conjugate, LynxTag-CQ_GREEN, as a Marker for Chloroquine Resistance and Uptake in a 96-Well Plate Assay

Cheryl C. Y. Loh, Rossarin Suwanarusk, [ ... ], Larry M. C. Chow

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