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Microsomes

Dual effects of indoxyl sulfate on modulation of human hepatic CYP3A activity, with individual differences

Masao Togao, Naoyuki Asakawa, Gaku Wagai, Yuki Ohta-Takada, Jun Otsuka, Minoru Ando, Akinobu Kurita, Koji Kawakami

published 10 Jul 2025

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In vitro safety evaluation of dopamine D₃R antagonist, R-VK4-116, as a potential medication for the treatment of opioid use disorder

Rahul M. Nandre, Amy Hauck Newman, Pramod S. Terse

published 16 Dec 2024

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Identification and quantification of the molecular species of bilirubin BDG, BMG and UCB by LC‒MS/MS in hyperbilirubinemic human serum

Stephany M. Castillo-Castañeda, Liliana Rivera-Espinosa, Josefina Gómez-Garduño, Jacqueline Cordova-Gallardo, Juan Luis Chávez-Pacheco, Nahum Méndez-Sánchez

published 19 Nov 2024

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The effects of CYP2B6 inactivators on the metabolism of ciprofol

Ming Lu, Xiaorui Zhang, Wenli Li, Xiangchen Li, Shan Li, Xiaoyu Yin, Zhiqing Zhang

published 29 Jul 2024

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Pharmacokinetic profile of oral and subcutaneous administration of paracetamol in the koala (Phascolarctos cinereus) and prediction of its analgesic efficacy

Merran Govendir, Larry Vogelnest, Amanda J. Shapiro, Caroline Marschner, Benjamin Kimble

published 17 Apr 2024

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Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization

Stephanie E. Martinez, Amit V. Pandey, Tania E. Perez Jimenez, Zhaohui Zhu, Michael H. Court

published 01 Feb 2024

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Impact of valproic acid on busulfan pharmacokinetics: In vitro assessment of potential drug-drug interaction

Bashayer F. Al-Enezi, Nada Al-Hasawi, Kamal M. Matar

published 25 Jan 2023

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Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn²⁺-dependent amidases

Jae Kyo Yi, Ruijuan Xu, Lina M. Obeid, Yusuf A. Hannun, Michael V. Airola, Cungui Mao

published 01 Sep 2022

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Glycyrrhiza uralensis promote the metabolism of toxic components of Aconitum carmichaeli by CYP3A and alleviate the development of chronic heart failure

Lulu Ni, Ping Miao, Jian Jiang, Fang Wan, Jiangan Li, Min Ai, Lingzhong Kong, Su Tu

published 27 Jun 2022

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Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis

Saumel Pérez-Rodriguez, María de Jesús Ramírez-Lira, Tune Wulff, Bjørn Gunnar Voldbor, Octavio T. Ramírez, Mauricio A. Trujillo-Roldán, Norma A. Valdez-Cruz

published 25 Aug 2020

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Hydrogenosomal tail-anchored proteins are targeted to both mitochondria and ER upon their expression in yeast cells

Andrè Ferdigg, Kai S. Dimmer, Doron Rapaport, Daniela G. Vitali

published 20 Aug 2020

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In vitro hepatic metabolism of mefloquine using microsomes from cats, dogs and the common brush-tailed possum (Trichosurus vulpecula)

Aaron Michael Izes, Benjamin Kimble, Jacqueline Marie Norris, Merran Govendir

published 14 Apr 2020

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Functions of mountain pine beetle cytochromes P450 CYP6DJ1, CYP6BW1 and CYP6BW3 in the oxidation of pine monoterpenes and diterpene resin acids

Christine C. Chiu, Christopher I. Keeling, Hannah M. Henderson, Joerg Bohlmann

published 09 May 2019

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