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Lysosomes

The role of reactive oxygen intermediates in the intracellular fate of Leptospira interrogans in the macrophages of different hosts

Shijun Li, Peili Li, [ ... ], Jie Yan

RNF41 interacts with the VPS52 subunit of the GARP and EARP complexes

Delphine Masschaele, Leentje De Ceuninck, [ ... ], Jan Tavernier

Ectopic overexpression of LAPTM5 results in lysosomal targeting and induces Mcl-1 down-regulation, Bak activation, and mitochondria-dependent apoptosis in human HeLa cells

Do Youn Jun, Hyejin Kim, [ ... ], Young Ho Kim

A tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies

Ryan D. Geraets, Logan M. Langin, [ ... ], David A. Pearce

Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1

Alfred L. Yergey, Paul S. Blank, [ ... ], Allan J. Darling

Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling

Emmanuel C. Patin, Anna C. Geffken, [ ... ], Ulrich E. Schaible

Transmembrane domain quality control systems operate at the endoplasmic reticulum and Golgi apparatus

Kit Briant, Nicholas Johnson, Eileithyia Swanton

Chronic environmental stress enhances tolerance to seasonal gradual warming in marine mussels

Ionan Marigómez, Maria Múgica, Urtzi Izagirre, Inna M. Sokolova

Lysosomal adaptation: How cells respond to lysosomotropic compounds

Shuyan Lu, Tae Sung, [ ... ], Bart A. Jessen

Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS

Xianzhi Qu, Jiyao Sheng, [ ... ], Liankun Sun

Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5

Joshi Stephen, Tadafumi Yokoyama, [ ... ], May Christine V. Malicdan

Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings

Xuefang Pan, Yanting Wang, [ ... ], Alexey V. Pshezhetsky

The Salmonella effector SseJ disrupts microtubule dynamics when ectopically expressed in normal rat kidney cells

Sally A. Raines, Michael R. Hodgkinson, Adam A. Dowle, Paul R. Pryor

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