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Lysosomes

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease

Andrea N. Crivaro, Juan M. Mucci, [ ... ], Paula A. Rozenfeld

The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418

Michael W. Ferguson, Chloe A. N. Gerak, [ ... ], Michel Roberge

Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)

Laura Lee, Richard Seager, [ ... ], Jeremy M. Henley

Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis

Lixiao Che, Xingyuan Yang, [ ... ], Chunying Du

Human Marfan and Marfan-like Syndrome associated mutations lead to altered trafficking of the Type II TGFβ receptor in Caenorhabditis elegans

Jing Lin, Mehul Vora, [ ... ], Richard W. Padgett

CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans

Brian J. Thomas, Ira E. Wight, [ ... ], Cliff J. Luke

Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo

James Dylewski, Evgenia Dobrinskikh, [ ... ], Judith Blaine

Control of basal autophagy rate by vacuolar peduncle

Marc Bourouis, Magali Mondin, Aurore Dussert, Pierre Leopold

Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes

Katarina Trajkovic, Clarissa Valdez, Daniel Ysselstein, Dimitri Krainc

The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy

Olga Biskou, Victor Casanova, [ ... ], Craig Stevens

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy

Tung-Cheng Chang, Po-Li Wei, [ ... ], Yu-Jia Chang

BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis

Gouri Yogalingam, Amanda R. Luu, [ ... ], Jonathan H. LeBowitz

Propyl gallate inhibits hepatocellular carcinoma cell growth through the induction of ROS and the activation of autophagy

Po-Li Wei, Chien-Yu Huang, Yu-Jia Chang

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