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Liver fibrosis

Evaluation of the mechanism underlying melatonin action in cholestatic liver disease treatment via network pharmacology, molecular docking, and in vivo experiments

Tao Li, Jiang ZhenYu, Wang Jing

published 27 Feb 2026

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Integrating phytochemical analysis and experimental validation of Ziziphus jujuba seed powder and oil to ameliorate CCl_4-induced liver fibrosis in sprague dawley rats

Laiba Tanvir, Khurram Afzal, Asad Abbas, Adnan Amjad, Talha Bin Iqbal, Naeem Sarwar, Rameen Naeem, Ayman Furqan, Bipindra Pandey

published 20 Feb 2026

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Genetic ablation of interleukin-17A augments fibrosis in a mouse model of cholestatic liver injury

Takashi Kitagataya, Anuradha Krishnan, Kirsta E. Olson, Florencia Gutierrez, Michelle Baez-Faria, Maria Eugenia Guicciardi, Kevin D. Pavelko, Adiba I. Azad, Gregory J. Gores

published 06 Feb 2026

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Adoption and validation of the European Association for the Study of the Liver algorithm for the noninvasive diagnosis of advanced fibrosis in metabolic dysfunction-associated steatotic liver disease in low-resource South Asian settings

Chamila Mettananda, Chamila Ranawaka, Thimira Egodage, Channaka Dantanarayana, Rumal Fernando, Lakmali Ranaweera, Dulani Kottahachchi, Shirom Siriwardhana, Arunasalam Pathmeswaran, Anuradha Dassanayake, Janaka de Silva

published 06 Feb 2026

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Ursolic acid alleviates liver injury in diabetic mice induced by high-fat diet combined with streptozotocin via the NLRP3 signaling pathway

Xinyan Wang, Ruyu Ma, Di Lou, Hanbing Li, Minyou Qi

published 04 Feb 2026

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Intestinal decontamination with rifaximin attenuates LSEC dysfunction and liver fibrosis in mice

Tingting Su, Sanchuan Lai, Hongtan Chen

published 23 Jan 2026

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Development of a novel scoring system to determine the optimal timing of esophagogastroduodenoscopy following portosystemic shunt occlusion

Tatsuro Nishimura, Aika Kirihara, Maho Egusa, Natsuko Nishiyama, Tsuyoshi Fujioka, Daiki Kawamoto, Ryo Sasaki, Norikazu Tanabe, Issei Saeki, Toshihiko Matsumoto, Tsuyoshi Ishikawa, Taro Takami

published 20 Jan 2026

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Fibrosis-4 and 3 indices are independently associated with annual hemoglobin decline in individuals with metabolic disorders: A hospital-based retrospective cohort study

Taiki Hori, Ken-ichi Aihara, Yutaka Kawano, Takeshi Watanabe, Yousuke Kaneko, Saki Kawata, Kazuma Shimizu, Minae Hosoki, Kensuke Mori, Toshiki Otoda, Tomoyuki Yuasa, Ken-ichi Matsuoka, Shingen Nakamura

published 12 Dec 2025

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Factors influencing effective decrease of controlled attenuation parameters in metabolic-associated steatotic liver disease: A multilevel linear regression analysis at Vajira Hospital

Sonsawan Sangprasert, Ratchaneewan Kwancharoen, Witchakorn Ruamtawee, Supatsri Sethasine

published 03 Dec 2025

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Combining transcriptomics with network pharmacology to explore the mechanism of Yiqi Huoxue decoction against liver fibrosis

Yao-Yao Mao, Ke Zhang, Dan-Dan Zhao, Jia-Wei Cui, Zhan-Dong Lin, Cong-Yue Zhang, Yue-Min Nan

published 26 Nov 2025

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MAFLD in Egyptian non-dialysis CKD Patients: Frequency, fibrosis severity, and risk factors

Zienab M. Saad, Hesham K. H. Keryakos, Hala A. Hassanin, Mahmoud M. Higazi, Manar M. Sayed, Doaa E. Ismail, Safaa M. Abdelhalim

published 24 Nov 2025

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Association between non-invasive biomarkers and quality of life in Primary Sclerosing Cholangitis

Jingyu Dai, Emmanuel Selvaraj, Emma L. Culver, Adam Bailey, Michael Brady, Michael Pavlides, Jose Leal

published 12 Nov 2025

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Predictive value of neutrophil to lymphocyte ratio for clinical outcomes in liver cirrhosis: A systematic review and meta-analysis

Jingjing Lin, Mengna Huang, Lina Shen

published 04 Nov 2025

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