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Library screening

Identification and validation of genes encoding humoral specificity for the chemical allergen toluene diisocyanate

Adam V. Wisnewski, Jian Liu

published 26 Feb 2026

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Repurposing antiviral agents against mucormycosis

Ammar A. Khan, Nour M. AlKashef, Mohamed N. Seleem

published 18 Feb 2026

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Screening a library of antibacterial compounds leads to discovery of novel inhibitors for Neisseria gonorrhoeae and Chlamydia trachomatis

Abdallah S. Abdelsattar, Nader S. Abutaleb, Mohamed N. Seleem

published 06 Feb 2026

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Computational repurposing of approved drugs targeting KRAS G12D and EGFR for colorectal cancer therapy

Walaa Ibraheem, Fatima Alsheikh, Abdulrahim A. Alzain, Bhoomendra A. Bhongade, Laila Ejaz, Hamnah Baig, Robert C. Robinson, Mohamed El-Tanani

published 28 Jan 2026

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Auranofin, identified by FDA-approved drug library screening, inhibits HBs antigen secretion via lysosomal damage

Akiyoshi Shimoda, Kazuhiro Murai, Hayato Hikita, Satoshi Minami, Takayuki Miyake, Shinji Kuriki, Emi Sometani, Jihyun Sung, Satoshi Shigeno, Yuichiro Higuchi, Kazuki Maesaka, Kumiko Shirai, Yuki Tahata, Yoshinobu Saito, Takahiro Kodama, Takeshi Takahashi, Hiroshi Suemizu, Tetsuo Takehara

published 16 Jan 2026

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Gender-transformative health promotion interventions for linking and retaining tuberculosis-diagnosed adult men in care in sub-Saharan Africa: A scoping review protocol

Siyabonga Kave, Yandisa Sikweyiya, Nelisiwe Khuzwayo

published 08 Jan 2026

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Analytical validation of a hybrid-approach combining tumor-informed and tumor-agnostic bespoke ctDNA panel assay for the sensitive detection of minimal residual disease

Sunghoon Heo, Seon-Kyu Ham, Hayoon Lee, Bom Han, Hanseong Roh, Seongmun Jeong, Hwang-Phill Kim, Duhee Bang, Sang-Hyun Song, Tae-You Kim

published 10 Nov 2025

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Computational structural studies of SGLT2-related polypharmacy

Aled Lloyd, Karl Austin-Muttitt, Jonathan G.L. Mullins

published 17 Oct 2025

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Isolation and characterization of a Chlamydia muridarum tc0237 mutant from a genetic screen that is attenuated in epithelial cells

Kaylee R. Jacobs, Caleb M. Ardizzone, Arkaprabha Banerjee, Evelyn Toh, Xiaoli Zhang, David E. Nelson

published 05 Aug 2025

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scFv intrabody targeting wildtype TDP-43 presents protective effects in a cellular model of TDP-43 proteinopathy

Yara Al Ojaimi, Rudolf Hergesheimer, Anna A. Chami, Hugo Alarcan, Johanna Augros, Audrey Dangoumau, Shanez Haouari, Jérôme Bourgeais, Antoine Lefevre, Samira Osman, Patrick Emond, Patrick Vourc’h, Christian R. Andres, Philippe Corcia, Olivier Herault, Pierre Martineau, Débora Lanznaster, Hélène Blasco

published 04 Aug 2025

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Identification of the Francisella novicida FTN_0096 as a factor involved in intracellular replication and host response

Dhandy Koesoemo Wardhana, Takashi Shimizu, Kenta Watanabe, Akihiko Uda, Masahisa Watarai

published 01 Aug 2025

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Enzymatic characterization and polyurethane biodegradation assay of two novel esterases isolated from a polluted river

Arianna Soto-Hernández, Luis Felipe Muriel-Millán, Adolfo Gracia, Alejandro Sánchez-Flores, Liliana Pardo-López

published 23 Jul 2025

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Association of microtubule destabilization with platelet yields in terminally differentiating hiPSC-derived megakaryocyte lines

Emiri Nakamura, Yasuo Harada, Trevor Bingham, Christian Skorik, Anjali Jha, John Atwater, Natsumi Higashi, Kosuke Fujio, Mariko Ishiguro, Haruki Okamoto, Leonard I. Zon, George Q. Daley, Andrew L. Frelinger, Koji Eto, Thorsten M. Schlaeger

published 25 Jun 2025

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