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Library screening

High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells

Danielle L. Schmitt, Patricia Dranchak, [ ... ], Songon An

Development and application of a qPCR-based genotyping assay for Ophidiomyces ophidiicola to investigate the epidemiology of ophidiomycosis

Ellen Haynes, Jeffrey Lorch, Matthew C. Allender

SUNi mutagenesis: Scalable and uniform nicking for efficient generation of variant libraries

Taylor L. Mighell, Ignasi Toledano, Ben Lehner

In-vitro high-throughput library screening—Kinetics and molecular docking studies of potent inhibitors of α-glucosidase

Majid Ali, Khuram Malik, [ ... ], Khaled S. Alshaibari

High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds

Conall Sauvey, Ittipat Meewan, [ ... ], Ruben Abagyan

In silico elucidation of potential drug targets against oxygenase domain of Human eNOS Dysfunction

Abbeha Malik, Muhammad Nasir Iqbal, [ ... ], Sheikh Arslan Sehgal

Tannic acid, an IL-1β-direct binding compound, ameliorates IL-1β-induced inflammation and cartilage degradation by hindering IL-1β-IL-1R1 interaction

Hae-Ri Lee, Young-Jin Jeong, [ ... ], Tae-Hwe Heo

Optimised protocol for monitoring SARS-CoV-2 in wastewater using reverse complement PCR-based whole-genome sequencing

Harry T. Child, Paul A. O’Neill, [ ... ], Aaron R. Jeffries

Deciphering the relational dynamics of AF-2 domain of PAN PPAR through drug repurposing and comparative simulations

Fouzia Gul, Nousheen Parvaiz, Syed Sikander Azam

Novel carbon skeletons activate human NicotinAMide Phosphoribosyl Transferase (NAMPT) enzyme in biochemical assay

Karen H. Almeida, Lisbeth Avalos-Irving, [ ... ], Silvia Yanez

Characterizing the consensus residue specificity and surface of BCL-2 binding to BH3 ligands using the Knob-Socket model

Jennifer Yi, Vivian Kellner, [ ... ], Jerry Tsai

Pandemic Response Box^® library as a source of antifungal drugs against Scedosporium and Lomentospora species

Rodrigo Rollin-Pinheiro, Mariana Ingrid Dutra da Silva Xisto, [ ... ], Eliana Barreto-Bergter

Repositioning of anti-dengue compounds against SARS-CoV-2 as viral polyprotein processing inhibitor

Leena H. Bajrai, Arwa A. Faizo, [ ... ], Esam I. Azhar

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