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Library screening

Identification of triciribine as a novel myeloid cell differentiation inducer

Souma Suzuki, Susumu Suzuki, [ ... ], Shinichiro Takahashi

Traffic trajectory data analysis technology based on HMM model map matching algorithm

Mingkang Sun, Xiang Li

A novel micellular fluorogenic substrate for quantitating the activity of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma (PLCγ) enzymes

Ramya Visvanathan, Tadanobu Utsuki, [ ... ], Karson S. Putt

Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform

Lijuan Zhou, Fei Cai, [ ... ], Yingnan Zhang

TTLL12 has a potential oncogenic activity, suppression of ligation of nitrotyrosine to the C-terminus of detyrosinated α-tubulin, that can be overcome by molecules identified by screening a compound library

Amit Deshpande, Jan Brants, [ ... ], Bohdan Wasylyk

Expanding the DNA editing toolbox: Novel lambda integrase variants targeting microalgal and human genome sequences

Jia Wei Siau, Asim Azhar Siddiqui, [ ... ], John F. Ghadessy

Exploring NCATS in-house biomedical data for evidence-based drug repurposing

Fang Liu, Andrew Patt, [ ... ], Qian Zhu

Chemobiosis reveals tardigrade tun formation is dependent on reversible cysteine oxidation

Amanda L. Smythers, Kara M. Joseph, [ ... ], Leslie M. Hicks

Differences in the gut microbiota between Gurkhas and soldiers of British origin

Thomas D. Troth, Ross S. McInnes, [ ... ], Willem van Schaik

A full-document analysis of the semantic relation between European Public Assessment Reports and EMA guidelines using a BERT language model

Erik Bergman, Anna Maria Gerdina Pasmooij, Peter G. M. Mol, Gabriel Westman

Computational exploration of novel ROCK2 inhibitors for cardiovascular disease management; insights from high-throughput virtual screening, molecular docking, DFT and MD simulation

Iqra Ali, Muhammad Nasir Iqbal, [ ... ], Abdul Rauf Siddiqi

Hunting for the elusive target antigen in gestational alloimmune liver disease (GALD)

Klaus Rieneck, Karen Koefoed Rasmussen, [ ... ], Morten Hanefeld Dziegiel

Targeting Filamenting temperature-sensitive mutant Z (FtsZ) with bioactive phytoconstituents: An emerging strategy for antibacterial therapy

Bader Saud Alotaibi

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